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Optics Letters


  • Editor: Alan E. Willner
  • Vol. 38, Iss. 20 — Oct. 15, 2013
  • pp: 4142–4145

Toward transduodenal diffuse optical tomography of proximal pancreas

Daqing Piao, Kenneth E. Bartels, Russell G. Postier, G. Reed Holyoak, and Jerry W. Ritchey  »View Author Affiliations

Optics Letters, Vol. 38, Issue 20, pp. 4142-4145 (2013)

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We demonstrate the feasibility of diffuse optical tomography (DOT) of the proximal pancreas by using optical applicator channels deployed longitudinally along the exterior surface of a duodenoscope. As the duodenum that nearly encircles the proximal pancreas forms a natural “C-loop” that is approximately three-quarters of a circle of 5–6 cm in diameter, a multichannel optical applicator attached to a duodenoscope has the potential to perform transduodenal DOT sampling of the bulk proximal pancreas wherein most cancers and many cystic lesions occur. The feasibility of transduodenal DOT is demonstrated on normal porcine pancreas tissues containing an introduced gelatinous inclusion of approximately 3 cm in diameter, by using nine source channels and six detector channels attached to a duodenoscope. Concurrent ultrasonography of the gelatinous inclusion in the porcine pancreas parenchyma provided a coarse, albeit indispensable, anatomic prior to transduodenal DOT in reconstructing a contrast of optical properties in the pancreas.

© 2013 Optical Society of America

OCIS Codes
(170.2150) Medical optics and biotechnology : Endoscopic imaging
(170.2680) Medical optics and biotechnology : Gastrointestinal
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.6960) Medical optics and biotechnology : Tomography

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: June 26, 2013
Revised Manuscript: September 8, 2013
Manuscript Accepted: September 11, 2013
Published: October 10, 2013

Daqing Piao, Kenneth E. Bartels, Russell G. Postier, G. Reed Holyoak, and Jerry W. Ritchey, "Toward transduodenal diffuse optical tomography of proximal pancreas," Opt. Lett. 38, 4142-4145 (2013)

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