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Optics Letters

Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Editor: Alan E. Willner
  • Vol. 38, Iss. 21 — Nov. 1, 2013
  • pp: 4433–4436

Angle independent flow assessment with bidirectional Doppler optical coherence tomography

Cedric Blatter, Branislav Grajciar, Leopold Schmetterer, and Rainer A. Leitgeb  »View Author Affiliations


Optics Letters, Vol. 38, Issue 21, pp. 4433-4436 (2013)
http://dx.doi.org/10.1364/OL.38.004433


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Abstract

Bidirectional Doppler optical coherence tomography is a stable and accurate method to extract the absolute velocity of vessels close to perpendicular to the optical axis by illuminating the sample under two different angles. However it requires knowledge of the vessel angle in the en face plane. In this Letter, we demonstrate that a direct calculation of the flow out of bidirectional Doppler cross sections perpendicular to the illumination plane is independent of that angle and of the Doppler angle, thereby improving the accuracy and flexibility of that technique. We validate our approach with an in vitro experiment and in vivo measurements of a human retinal vessel and discuss the practical limitations of this approach. The method yields accurate flow values for most vascular plexuses without precise knowledge of the vessel orientation. The precision gradually decreases for larger en face angles.

© 2013 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(170.4460) Medical optics and biotechnology : Ophthalmic optics and devices
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(280.2490) Remote sensing and sensors : Flow diagnostics
(170.2655) Medical optics and biotechnology : Functional monitoring and imaging

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: August 6, 2013
Manuscript Accepted: September 6, 2013
Published: October 30, 2013

Virtual Issues
Vol. 9, Iss. 1 Virtual Journal for Biomedical Optics

Citation
Cedric Blatter, Branislav Grajciar, Leopold Schmetterer, and Rainer A. Leitgeb, "Angle independent flow assessment with bidirectional Doppler optical coherence tomography," Opt. Lett. 38, 4433-4436 (2013)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-38-21-4433

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