OSA's Digital Library

Optics Letters

Optics Letters


  • Editor: Alan E. Willner
  • Vol. 38, Iss. 22 — Nov. 15, 2013
  • pp: 4671–4674

Ultra-wideband three-dimensional optoacoustic tomography

Jérôme Gateau, Andrei Chekkoury, and Vasilis Ntziachristos  »View Author Affiliations

Optics Letters, Vol. 38, Issue 22, pp. 4671-4674 (2013)

View Full Text Article

Enhanced HTML    Acrobat PDF (437 KB)

Browse Journals / Lookup Meetings

Browse by Journal and Year


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools



Broadband optoacoustic waves generated by biological tissues excited with nanosecond laser pulses carry information corresponding to a wide range of geometrical scales. Typically, the frequency content present in the signals generated during optoacoustic imaging is much larger compared to the frequency band captured by common ultrasonic detectors, the latter typically acting as bandpass filters. To image optical absorption within structures ranging from entire organs to microvasculature in three dimensions, we implemented optoacoustic tomography with two ultrasound linear arrays featuring a center frequency of 6 and 24 MHz, respectively. In the present work, we show that complementary information on anatomical features could be retrieved and provide a better understanding on the localization of structures in the general anatomy by analyzing multi-bandwidth datasets acquired on a freshly excised kidney.

© 2013 Optical Society of America

OCIS Codes
(110.5120) Imaging systems : Photoacoustic imaging
(110.6960) Imaging systems : Tomography
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.6935) Medical optics and biotechnology : Tissue characterization

ToC Category:
Imaging Systems

Original Manuscript: September 2, 2013
Manuscript Accepted: October 1, 2013
Published: November 8, 2013

Virtual Issues
Vol. 9, Iss. 1 Virtual Journal for Biomedical Optics

Jérôme Gateau, Andrei Chekkoury, and Vasilis Ntziachristos, "Ultra-wideband three-dimensional optoacoustic tomography," Opt. Lett. 38, 4671-4674 (2013)

Sort:  Author  |  Year  |  Journal  |  Reset  


  1. V. Ntziachristos, Nat. Methods 7, 603 (2010).
  2. P. Beard, Interface Focus 1, 602 (2011). [CrossRef]
  3. L. V. Wang and S. Hu, Science 335, 1458 (2012). [CrossRef]
  4. G. J. Diebold and T. Sun, Acta Acust. United Acust. 80, 339 (1994).
  5. M. Xu and L. V. Wang, Phys. Rev. E 67, 056605 (2003). [CrossRef]
  6. D. Razansky, A. Buehler, and V. Ntziachristos, Nature Protocols 6, 1121 (2011). [CrossRef]
  7. H. P. Brecht, R. Su, M. Fronheiser, S. A. Ermilov, A. Conjusteau, and A. A. Oraevsky, J. Biomed. Opt. 14, 064007 (2009). [CrossRef]
  8. J. Gateau, M. A. A. Caballero, A. Dima, and V. Ntziachristos, Med. Physics 40, 013302 (2013). [CrossRef]
  9. R. A. Kruger, R. B. Lam, D. R. Reinecke, S. P. Del Rio, and R. P. Doyle, Med. Physics 37, 6096 (2010). [CrossRef]
  10. D. Razansky, M. Distel, C. Vinegoni, R. Ma, N. Perrimon, R. W. Koster, and V. Ntziachristos, Nat. Photonics 3, 412 (2009).
  11. M. Omar, J. Gateau, and V. Ntziachristos, Opt. Lett. 38, 2472 (2013). [CrossRef]
  12. J. Laufer, P. Johnson, E. Zhang, B. Treeby, B. Cox, B. Pedley, and P. Beard, J. Biomed. Opt. 17, 056016 (2012). [CrossRef]
  13. R. Ma, S. Söntges, S. Shoham, V. Ntziachristos, and D. Razansky, Biomed. Opt. Express 3, 1724 (2012). [CrossRef]
  14. K. Geng, W. Xueding, S. George, and V. W. Lihong, Phys. Medicine Biol. 49, 1329 (2004). [CrossRef]
  15. M. Schünke, E. Schulte, U. Schumacher, L. M. Ross, and E. D. Lamperti, Thieme Atlas of Anatomy: Neck and Internal Organs (Thieme Medical, 2010).

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


Fig. 1. Fig. 2. Fig. 3.

Supplementary Material

» Media 1: AVI (3093 KB)     
» Media 2: AVI (2611 KB)     

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited