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Optics Letters

Optics Letters


  • Editor: Alan E. Willner
  • Vol. 38, Iss. 22 — Nov. 15, 2013
  • pp: 4845–4848

Quantitative phase imaging via Fourier ptychographic microscopy

Xiaoze Ou, Roarke Horstmeyer, Changhuei Yang, and Guoan Zheng  »View Author Affiliations

Optics Letters, Vol. 38, Issue 22, pp. 4845-4848 (2013)

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Fourier ptychographic microscopy (FPM) is a recently developed imaging modality that uses angularly varying illumination to extend a system’s performance beyond the limit defined by its optical components. The FPM technique applies a novel phase-retrieval procedure to achieve resolution enhancement and complex image recovery. In this Letter, we compare FPM data to theoretical prediction and phase-shifting digital holography measurement to show that its acquired phase maps are quantitative and artifact-free. We additionally explore the relationship between the achievable spatial and optical thickness resolution offered by a reconstructed FPM phase image. We conclude by demonstrating enhanced visualization and the collection of otherwise unobservable sample information using FPM’s quantitative phase.

© 2013 Optical Society of America

OCIS Codes
(100.5070) Image processing : Phase retrieval
(120.5050) Instrumentation, measurement, and metrology : Phase measurement
(180.0180) Microscopy : Microscopy

ToC Category:

Original Manuscript: August 1, 2013
Revised Manuscript: September 26, 2013
Manuscript Accepted: October 15, 2013
Published: November 14, 2013

Virtual Issues
Vol. 9, Iss. 1 Virtual Journal for Biomedical Optics

Xiaoze Ou, Roarke Horstmeyer, Changhuei Yang, and Guoan Zheng, "Quantitative phase imaging via Fourier ptychographic microscopy," Opt. Lett. 38, 4845-4848 (2013)

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