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Dual-modality needle probe for combined fluorescence imaging and three-dimensional optical coherence tomography |
Optics Letters, Vol. 38, Issue 3, pp. 266-268 (2013)
http://dx.doi.org/10.1364/OL.38.000266
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Abstract
To the best of our knowledge, we present the first needle probe for combined optical coherence tomography (OCT), and fluorescence imaging. The probe uses double-clad fiber (DCF) that guides the OCT signal and fluorescence excitation light in the core and collects and guides the returning fluorescence in the large-diameter multimode inner cladding. It is interfaced to a 1310 nm swept-source OCT system that has been modified to enable simultaneous 488 nm fluorescence excitation and
© 2013 Optical Society of America
OCIS Codes
(060.2370) Fiber optics and optical communications : Fiber optics sensors
(170.2150) Medical optics and biotechnology : Endoscopic imaging
(170.2520) Medical optics and biotechnology : Fluorescence microscopy
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.4500) Medical optics and biotechnology : Optical coherence tomography
ToC Category:
Medical Optics and Biotechnology
History
Original Manuscript: October 24, 2012
Revised Manuscript: December 7, 2012
Manuscript Accepted: December 16, 2012
Published: January 16, 2013
Virtual Issues
Vol. 8, Iss. 3 Virtual Journal for Biomedical Optics
Citation
Dirk Lorenser, Bryden C. Quirk, Mathieu Auger, Wendy-Julie Madore, Rodney W. Kirk, Nicolas Godbout, David D. Sampson, Caroline Boudoux, and Robert A. McLaughlin, "Dual-modality needle probe for combined fluorescence imaging and three-dimensional optical coherence tomography," Opt. Lett. 38, 266-268 (2013)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-38-3-266
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