OSA's Digital Library

Optics Letters

Optics Letters

| RAPID, SHORT PUBLICATIONS ON THE LATEST IN OPTICAL DISCOVERIES

  • Editor: Xi-Cheng Zhang
  • Vol. 39, Iss. 12 — Jun. 15, 2014
  • pp: 3472–3475

Speckle statistics in OCT images: Monte Carlo simulations and experimental studies

Mikhail Yu. Kirillin, Golnaz Farhat, Ekaterina A. Sergeeva, Michael C. Kolios, and Alex Vitkin  »View Author Affiliations


Optics Letters, Vol. 39, Issue 12, pp. 3472-3475 (2014)
http://dx.doi.org/10.1364/OL.39.003472


View Full Text Article

Enhanced HTML    Acrobat PDF (514 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

The speckle pattern of an optical coherence tomography (OCT) image carries potentially useful sample information that may assist in tissue characterization. Recent biomedical results in vivo indicate that the distribution of signal intensities within an OCT tissue image is well described by a log-normal-like (Gamma) function. To fully understand and exploit this finding, an OCT Monte Carlo model that accounts for speckle effects was developed. The resultant Monte Carlo speckle statistics predictions agree well with experimental OCT results from a series of control phantoms with variable scattering properties; the Gamma distribution provides a good fit to the theoretical and experimental results. The ability to quantify subresolution tissue features via OCT speckle analysis may prove useful in diagnostic photomedicine.

© 2014 Optical Society of America

OCIS Codes
(030.6140) Coherence and statistical optics : Speckle
(100.2960) Image processing : Image analysis
(110.4500) Imaging systems : Optical coherence tomography
(290.4210) Scattering : Multiple scattering

ToC Category:
Coherence and Statistical Optics

History
Original Manuscript: March 12, 2014
Revised Manuscript: May 8, 2014
Manuscript Accepted: May 8, 2014
Published: June 5, 2014

Virtual Issues
Vol. 9, Iss. 8 Virtual Journal for Biomedical Optics

Citation
Mikhail Yu. Kirillin, Golnaz Farhat, Ekaterina A. Sergeeva, Michael C. Kolios, and Alex Vitkin, "Speckle statistics in OCT images: Monte Carlo simulations and experimental studies," Opt. Lett. 39, 3472-3475 (2014)
http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-39-12-3472

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited