We have developed a prototype ocular imaging system that integrates optical-resolution photoacoustic microscopy and high-frequency ultrasound imaging. The system can perform high-resolution ocular imaging from the anterior region down to the fundus. It has successfully imaged murine eyes in vivo, including iris, lens, retina, and retinal pigment epithelium. Our results demonstrate that this system shows strong potential for the diagnosis of ophthalmic diseases.
© 2014 Optical Society of America
Original Manuscript: December 30, 2013
Manuscript Accepted: March 8, 2014
Published: April 11, 2014
Vol. 9, Iss. 6 Virtual Journal for Biomedical Optics
Ning Wu, Shuoqi Ye, Qiushi Ren, and Changhui Li, "High-resolution dual-modality photoacoustic ocular imaging," Opt. Lett. 39, 2451-2454 (2014)