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Optical Materials Express

Optical Materials Express

  • Editor: David J. Hagan
  • Vol. 3, Iss. 2 — Feb. 1, 2013
  • pp: 157–165

Synthesis of green-emitting Pt8 nanoclusters for biomedical imaging by pre-equilibrated Pt/PAMAM (G4-OH) and mild reduction

Shin-ichi Tanaka, Koichi Aoki, Atsushi Muratsugu, Hidekazu Ishitobi, Takashi Jin, and Yasushi Inouye  »View Author Affiliations


Optical Materials Express, Vol. 3, Issue 2, pp. 157-165 (2013)
http://dx.doi.org/10.1364/OME.3.000157


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Abstract

We synthesized green-emitting platinum (Pt) nanoclusters (excitation: 460 nm, emission: 520 nm) by reducing Pt ions from pre-equilibrated Pt/fourth-generation poly(amidoamine) dendrimers (PAMAM (G4-OH)) complexes with a mild reductant. The structural characteristics of the resulting Pt nanoclusters, Pt8L8 (L = C2H2O2S), were determined by Electrospray ionization (ESI) mass spectroscopy. These nanoclusters possess a 28% quantum yield, which is higher than those of green-emitting Au and Ag nanoclusters. We also found that Pt nanoclusters have considerably low cytotoxicity and biocompatibility, and demonstrated that they could be used for biomedical imaging. This study provides the possibility to extend the photoluminescent wavelength of Pt nanoclusters to the near infrared region, which is ideal for biological imaging applications.

© 2013 OSA

OCIS Codes
(160.2540) Materials : Fluorescent and luminescent materials
(170.2520) Medical optics and biotechnology : Fluorescence microscopy
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(160.4236) Materials : Nanomaterials

ToC Category:
Fluorescent and Luminescent Materials

History
Original Manuscript: September 17, 2012
Revised Manuscript: November 8, 2012
Manuscript Accepted: November 8, 2012
Published: January 3, 2013

Citation
Shin-ichi Tanaka, Koichi Aoki, Atsushi Muratsugu, Hidekazu Ishitobi, Takashi Jin, and Yasushi Inouye, "Synthesis of green-emitting Pt8 nanoclusters for biomedical imaging by pre-equilibrated Pt/PAMAM (G4-OH) and mild reduction," Opt. Mater. Express 3, 157-165 (2013)
http://www.opticsinfobase.org/ome/abstract.cfm?URI=ome-3-2-157


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