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CLEO: Applications and Technology (2012)

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  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh1M.1
  • OSA Technical Digest (online)
  • Wax, Adam
  • We have developed several spectroscopic coherence imaging methods to detect pre-cancerous cells by isolating scattering signatures from specific tissue locations. We describe these...

  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh1M.2
  • OSA Technical Digest (online)
  • Aviles-Espinosa, Rodrigo; Ding, Ying; Cataluna, Maria Ana; Nikitichev, Daniil; Loza-Alvarez, Pablo; Rafailov, Edik
  • The requirement of less-expensive laser system for nonlinear bio-imaging applications can be addressed employing chip-sized devices. Preliminary studies using an amplified quantum-dot...

  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh1M.3
  • OSA Technical Digest (online)
  • Hoy, Christopher L; Ferhanoglu, Onur; Yildirim, Murat; Piyawattanametha, Wibool; Ra, Hyeju; Solgaard, Olav; Ben-Yakar, Adela
  • We present a 9.6-mm fiber-coupled probe for femtosecond laser microsurgery and nonlinear imaging. Towards enabling clinical use, we successfully reduced the volume of our earlier 18-mm...

  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh1M.4
  • OSA Technical Digest (online)
  • Pinon, Tessa M; Hirst, Linda S; Sharping, Jay E
  • We demonstrate a dual-beam fiber trap for optically stretching lipid vesicles encapsulated with poly(ethylene glycol) polymer solution. Vesicle deformations exhibit ranges of linear...

  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh1M.5
  • OSA Technical Digest (online)
  • Lin, Shiyun; Crozier, Kenneth B
  • We demonstrate an integrated system for particle trapping and sorting. Particles are pulled by optical forces onto a silicon microdonut, and circulate around it. Particle-induced...

  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh1M.6
  • OSA Technical Digest (online)
  • Kim, Kwang-Sung; Son, Joo-Hiuk
  • We present that the terahertz molecular imaging (TMI) technique can be applied to detection and movement of stem cells into the wound skin in vivo with employing nanoparticle probes.

  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh3L.1
  • OSA Technical Digest (online)
  • Tao, Lei; Sun, Kang; Miller, David J; Khan, Mohammad A; Zondlo, Mark A
  • A QCL laser based open-path sensor for N2O/CO achieves a sensitivity of 0.26 ppbv N2O and 0.24 ppbv CO in 1s. Optimizations including dual modulation amplitudes and inline reference...

  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh3L.2
  • OSA Technical Digest (online)
  • Wang, Wen E; Michel, Anna P; Wang, Lingxue; Nikodem, Michal; Tsai, Tracy R; Baeck, Mary L; Smith, James; Wysocki, Gerard
  • A 7.12 μm Quantum Cascade laser-based water vapor isotope spectrometer for the real time measurement of H<sub>2</sub>O<sup>16</sup>,...

  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh3L.3
  • OSA Technical Digest (online)
  • Tsai, Tracy R; Rose, Rebecca A; Weidmann, Damien; Macleod, Neil; Wysocki, Gerard
  • Retrieval of atmospheric vertical profiles of 5 molecules from spectra taken with 60MHz resolution external cavity quantum cascade laser heterodyne radiometer and 600MHz Fourier...

  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh3L.4
  • OSA Technical Digest (online)
  • Karpf, Andreas; Rao, Gottipaty N
  • Detection of NO2 at the ppb-level is demonstrated using a vibration-insensitive variation of cavity ring-down spectroscopy. Modulating the laser frequency and off-axis alignment...

  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh3L.5
  • OSA Technical Digest (online)
  • Keutsch, Frank; Paul, Joshua; Digangi, Joshua; Henry, Samuel
  • We present recent advances, combining novel laser technologies and spectroscopic methods, for high-sensitivity detection of volatile organic compounds within the context of the...

  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh3L.6
  • OSA Technical Digest (online)
  • Sun, Kang; Tao, Lei; Miller, David J; Khan, Mohammad A; Zondlo, Mark A
  • We demonstrate a real-time calibration of open-path ammonia sensing with an ethylene reference cell. Different harmonic WMS signals separate ethylene and ammonia so that ethylene...

  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh3L.7
  • OSA Technical Digest (online)
  • Miller, David J; Sun, Kang; Tao, Lei; Khan, Mohammad A; Zondlo, Mark A
  • An open-path quantum cascade laser atmospheric ammonia sensor is demonstrated in a range of field environments. The low power, compact sensor with 500pptv detection limit in 1s...

  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh4C.1
  • OSA Technical Digest (online)
  • Pogue, Brian
  • Integration of localized molecular spectroscopy into standard medical imaging instrumentation has been slow in developing, yet today there have been major developments which make it...

  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh4C.2
  • OSA Technical Digest (online)
  • Yazdanfar, Siavash
  • We describe handheld and minimally invasive imaging hardware, coupled with myelin-targeting contrast agents, to bring intraoperative fluorescence image-guided nerve labeling towards...

  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh4C.3
  • OSA Technical Digest (online)
  • Straub, Adam A; Howard, Scott S; Xu, Chris
  • We demonstrate a novel depth-resolved parallel-acquisition fluorescence lifetime imaging technique, and present in-vivo images of mouse brain. Analysis shows up to two...

  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh4C.4
  • OSA Technical Digest (online)
  • Benaron, David
  • The ability to detect and image biology at a level specific to the molecule, pathway, or cell is providing a new boom in biotechnology. Optics is playing a key role ...

  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh5A.1
  • OSA Technical Digest (online)
  • Zhang, Yuying; Murari, Kartikeya; Liang, Wenxuan; Xi, Jiefeng; Chen, Yongping; Li, Ming-Jun; Bhujwalla, Zaver; Glunte, Kristine; Li, Xingde
  • We report recent advances in ultrathin fiber-optic endomicroscopy technology with significant improvements on resolution and signal collection. Ex vivo and in vivo two-photon imaging...

  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh5A.2
  • OSA Technical Digest (online)
  • Ouzounov, Dimitre; Rivera, David R; Brown, Christopher M; Webb, Watt W; Xu, Chris
  • We present a dual modality microendoscope with a miniature, 9x optical zoom lens that is capable of large field-of-view (1.3 mm) reflectance imaging and high-resolution (0.57 um)...

  • CLEO: Applications and Technology (CLEO_AT) 2012 paper: ATh5A.3
  • OSA Technical Digest (online)
  • Lewicki, Rafal; Waclawek, Johannes; Jahjah, Mohammad; Ma, Yufei; Chrysostom, Engelene; Lendl, Bernhard; Tittel, Frank K
  • The development of a sensitive SO2 QEPAS-based sensor platform employing a CW DFB-QCL will be reported. A detection sensitivity of 100 ppbv was achieved with a 1-sec averaging time for...
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