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Biomedical Topical Meeting (2006)

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  • Biomedical Topical Meeting (BIO) 2006 paper: MA1
  • Technical Digest (CD)
  • Rector, David
  • Full-text article is not available.

  • Biomedical Topical Meeting (BIO) 2006 paper: MB1
  • Technical Digest (CD)
  • Hillman, Elizabeth M C; Bouchard, Matthew; Devor, Anna; de Crespigny, Alex; Boas, David A
  • We have developed and applied new optical technologies for imaging the brain’s neuronal and hemodynamic responses to stimulus, including 3D high-resolution Laminar Optical Tomography,...

  • Biomedical Topical Meeting (BIO) 2006 paper: MB3
  • Technical Digest (CD)
  • Heng, Xin; Erickson, David; Baugh, Larry R; Yaqoob, Zahid; Sternberg, Paul W; Psaltis, Demetri; Yang, Changhuei
  • We report the implementation of a novel microscope-on-a-chip system, termed the “Optofluidic Microscope (OFM)”. The OFM prototype is high resolution, compact and capable of...

  • Biomedical Topical Meeting (BIO) 2006 paper: MB4
  • Technical Digest (CD)
  • So, Peter T C; Pelet, Serge; Rahim, Nur Aida Abdul; Previte, Michael; Kamm, Roger D
  • Microanalysis incorporating fluorescence lifetime-resolved resonance energy transfer and fluorescence correlation spectroscopy allows the kinetics and the thermodynamics of protein...

  • Biomedical Topical Meeting (BIO) 2006 paper: MC1
  • Technical Digest (CD)
  • Laufer, Jan; Elwell, Clare; Delpy, Dave; Beard, Paul
  • Pulsed photoacoustic spectroscopy was used to make quantitative and spatially resolved measurements of blood oxygen saturation (SO2) in vitro with a performance comparable to that of a...

  • Biomedical Topical Meeting (BIO) 2006 paper: MC10
  • Technical Digest (CD)
  • Li, Ang; Kwong, Richard; Cerussi, Albert; Hayakawa, Carole; Tromberg, Bruce
  • The recovery of broadband diffuse optical spectra of both layers in a two-layer phantom is reported for the first time. The recovery uses a diffusion equation solution with relative...

  • Biomedical Topical Meeting (BIO) 2006 paper: MC2
  • Technical Digest (CD)
  • van der Voort, Marjolein; van Beek, Michiel; Lucassen, Gerald; de Bokx, Pieter; Rensen, Wouter; Engel, Jan
  • We have developed a non-invasive blood analysis method based on combined imaging and confocal Raman spectroscopy. With this technology, in-vivo Raman spectra can be obtained that...

  • Biomedical Topical Meeting (BIO) 2006 paper: MC3
  • Technical Digest (CD)
  • Sapozhnikova, Veronika; Kuranov, Roman; Prough, Donald; Cicenaite, Inga; Esenaliev, Rinat
  • The capability of optical coherence tomography (OCT) to predict blood glucose concentration changes within physiological range was studied in vivo. Accuracy of 2 mM in prediction of...

  • Biomedical Topical Meeting (BIO) 2006 paper: MC4
  • Technical Digest (CD)
  • Grant, P Ellen; Themelis, George; Arvin, Kara; Thaker, Sonal; Krishnamoorthy, Kalpathy K; Bortfeld, Heather; Franceschini, Maria Angela
  • To determine if quantitative regional StO2 and HbT measured with near infrared spectroscopy (NIRS) could detect differences between normal neonates and those with acute cerebral injury...

  • Biomedical Topical Meeting (BIO) 2006 paper: MC5
  • Technical Digest (CD)
  • Zhou, Chao; Durduran, Turgut; Yu, Guoqiang; Eucker, Stephanie; Friess, Stuart; Ichord, Rebecca; Margulies, Susan; Yodh, Arjun G
  • Diffuse optical techniques were used to continuously monitor hemodynamic changes in piglet brains after traumatic head injury. The potential for using all optical methods for long-term...

  • Biomedical Topical Meeting (BIO) 2006 paper: MC6
  • Technical Digest (CD)
  • Leung, Terence S; Tachtsidis, Ilias; Elwell, Clare E; Delpy, David T; Tisdall, Martin; Smith, Martin; Arridge, Simon
  • Using the Fick principle and a finite element model of light distribution, ICG boluses were simulated in a head model, showing measurable changes in cerebral blood flow using NIR...

  • Biomedical Topical Meeting (BIO) 2006 paper: MC7
  • Technical Digest (CD)
  • Shih, Wei-Chuan; Bechtel, Kate L; Feld, Michael S
  • We present a new technique, intrinsic Raman spectroscopy, which utilizes diffuse reflectance to correct sample turbidity-induced distortions in Raman spectra. This technique allows for...

  • Biomedical Topical Meeting (BIO) 2006 paper: MC8
  • Technical Digest (CD)
  • Brock, Robert S; Hu, Xin-Hua; Weidner, Douglas A; Mourant, Judith R; Lu, Jun Q
  • Mueller matrix elements of B-lymphocytes were obtained with reconstructed structures using a parallel FDTD code. By comparing with sphere models, we show that fine structure features...

  • Biomedical Topical Meeting (BIO) 2006 paper: MC9
  • Technical Digest (CD)
  • D'Andrea, Cosimo; Spinelli, Lorenzo; Bassi, Andrea; Giusto, Arianna; Contini, Davide; Swartling, Johannes; Torricelli, Alessandro; Cubeddu, Rinaldo
  • We have developed and experimentally validated, on tissue-simulating phantoms and in-vivo, a time-resolved spectral fitting analysis for direct evaluation of chromophore concentrations...

  • Biomedical Topical Meeting (BIO) 2006 paper: MD1
  • Technical Digest (CD)
  • Barbour, Randall L; Pei, Yaling; Graber, Harry L; Ansari, Rehman; Schmitz, Christoph H; Holzer, Matthew; Barry, Jeremy; Muller, Robert
  • We have developed an integrated DOT-EEG and behavioral recording system that provides, through a tethered head stage, concurrent recording in freely moving rats. Results show that...

  • Biomedical Topical Meeting (BIO) 2006 paper: MD10
  • Technical Digest (CD)
  • Yao, Xin-Cheng; George, John S
  • We demonstrated fast imaging of activation in isolated frog retina using intrinsic optical responses associated with electrophysiological function. Dynamic optical responses were...

  • Biomedical Topical Meeting (BIO) 2006 paper: MD2
  • Technical Digest (CD)
  • Franceschini, Maria Angela; Nissilä, Ilkka; Wu, Weicheng; Bonmassar, Giorgio; Boas, David A
  • In this work we investigated the relationship between electrical and hemodynamic responses relating to neuronal activation. To this aim diffuse optical imaging and...

  • Biomedical Topical Meeting (BIO) 2006 paper: MD3
  • Technical Digest (CD)
  • Chen, Yu; Aguirre, Aaron D; Ruvinskaya, Lana; Devor, Anna; Boas, David A; Fujimoto, James G
  • Simultaneous OCT and video microscopy were performed on rat somatosensory cortex during forepaw stimulation. Fractional changes in localized regions of OCT images reveal a functional...

  • Biomedical Topical Meeting (BIO) 2006 paper: MD4
  • Technical Digest (CD)
  • Gratton, G; Low, K A; Maclin, E L; Brumback, C R; Gordon, B; Fabiani, Monica
  • We recorded fast optical changes elicited by visual stimulation in occipital cortex from 19 young and 45 old human subjects. Faster propagation of activity from primary to secondary...

  • Biomedical Topical Meeting (BIO) 2006 paper: MD5
  • Technical Digest (CD)
  • Zeff, Benjamin W; Culver, Joseph P; Dehghani, Hamid
  • We present diffuse optical tomography of brain activity in the human visual cortex. A new, high-density imaging instrument improves spatial sampling and allows better discrimination of...
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