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Biomedical Optics (2012)

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  • Biomedical Optics (BIOMED) 2012 paper: BM2A.1
  • OSA Technical Digest
  • Hasan, Tayyaba
  • Advances in optical technologies combined with targeted molecular probes enable therapeutics optimization by earlier disease detection or by therapy monitoring. Photodynamic therapy...

  • Biomedical Optics (BIOMED) 2012 paper: BM2A.2
  • OSA Technical Digest
  • Zhang, Xuemei; Chen, Antony; Tsourkas, Andrew
  • Recently, we developed an oligonucleotide-based probe for imaging RNA in living cells, i.e. Ratiometric BiMolecular Beacons (RBMBs). RBMBs are highly sensitive, exhibit little/no...

  • Biomedical Optics (BIOMED) 2012 paper: BM2A.3
  • OSA Technical Digest
  • Chernomordik, Victor; Hassan, Moinuddin; Ardeshirpour, Yasaman; Zielinski, Rafal; Capala, Jacek; Gandjbakhche, Amir
  • Her2 overexpression in different carcinoma types is assessed in vivo (mouse model), using time sequences of fluorescence images after injection of HER2-specific fluorescent probes with...

  • Biomedical Optics (BIOMED) 2012 paper: BM2A.4
  • OSA Technical Digest
  • Goergen, Craig J; Chen, Howard H; Bogdanov, Alexei; Sosnovik, David E; Kumar, Anand T
  • Using a protease-activatable near-infrared probe, we demonstrate that lifetime-based time domain imaging can improve fluorescence contrast useful for detecting myocardial infarctions...

  • Biomedical Optics (BIOMED) 2012 paper: BM2A.5
  • OSA Technical Digest
  • Jin, Cheng; Lovell, Jonathan F; Zheng, Gang
  • Porphysomes are intrinsically multifunctional nanovesicles with unique structure-dependent fluorescence self-quenching and photothermal properties. We investigated imaging and...

  • Biomedical Optics (BIOMED) 2012 paper: BM2A.6
  • OSA Technical Digest
  • Solomon, Metasebya; Nothdurft, Ralph; Akers, Walter; Edwards, W Barry; Liang, Kexian; Xu, Baogang; Dehghani, Hamid; Tai, Yuan-Chuan; Achilefu, Sam; Culver, Joseph P
  • We integrated our fiber-based video-rate fluorescence diffuse optical tomography with a preclinical NanoSPECT/CT.This design permits visualization of anatomically co-registered...

  • Biomedical Optics (BIOMED) 2012 paper: BM2A.7
  • OSA Technical Digest
  • Pattani, Varun; Tunnell, James
  • Photothermal therapy was performed by targeting gold nanorods to two locations on cancer cells. We demonstrated a fluence rate threshold difference during therapy, suggesting certain...

  • Biomedical Optics (BIOMED) 2012 paper: BM2A.8
  • OSA Technical Digest
  • Yuan, Hsiangkuo; Khoury, Christopher; Fales, Andrew; Wilson, Christy; Grant, Gerald; Vo-Dinh, Tuan
  • Gold nanostars, with tunable plasmon in the near infrared tissue optic window, generate intense two-photon photoluminescence capable of in vitro cell labeling and in vivo particle...

  • Biomedical Optics (BIOMED) 2012 paper: BM2B.1
  • OSA Technical Digest
  • O'Donnell, Matthew; Wei, Chen-wei; Xia, Jinjun; Pelivanov, Ivan; Gao, Xiaohu; Hu, Xiaoge
  • Magnetic trapping and manipulation of polystyrene beads mimicking magnetically targeted circulating tumor cells (CTCs) has been demonstrated using magnetomotive photoacoustic (mmPA)...

  • Biomedical Optics (BIOMED) 2012 paper: BM2B.2
  • OSA Technical Digest
  • van der Steen, Ton
  • Article not available.

  • Biomedical Optics (BIOMED) 2012 paper: BM2B.3
  • OSA Technical Digest
  • Beard, Paul
  • 3D photoacoustic images of the vasculature in mice were obtained in vivo using a photoacoustic scanner based on a Fabry Perot polymer film ultrasound sensor and an attenuation...

  • Biomedical Optics (BIOMED) 2012 paper: BM2B.4
  • OSA Technical Digest
  • Yang, Joon-Mo; Favazza, Christopher; Chen, Ruimin; Yao, Junjie; Cai, Xin; Maslov, Konstantin; Zhou, Qifa; Shung, Kirk; Wang, Lihong V
  • Photoacoustic endoscopy provides unique functional information through its broad spectroscopic imaging capability. The imaging results presented here suggest its potential for use as a...

  • Biomedical Optics (BIOMED) 2012 paper: BM2B.5
  • OSA Technical Digest
  • Hussain, Altaf; Daoudi, Khalid; Hondebrink, Erwin; Steenbergen, Wiendelt
  • We propose a methodology to measure the absolute local absorption coefficient in biological tissue using photoacoustics in combination with reflection mode acousto-optics. We provide...

  • Biomedical Optics (BIOMED) 2012 paper: BM2B.6
  • OSA Technical Digest
  • Jiao, Shuliang; Zhang, Hao F
  • We combined photoacoustic ophthalmoscopy with autofluorescence imaging for simultaneous in vivo imaging of dual molecular contrasts in the retina using single light source. The dual...

  • Biomedical Optics (BIOMED) 2012 paper: BM2B.7
  • OSA Technical Digest
  • Chen, Yun-Sheng; Homan, Kimberly; Xu, David; Frey, Wolfgang; Emelianov, Stanislav
  • The feasibility of photoacoustic imaging in ex-vivo liver tissue was demonstrated. Studies were performed using a pulsed laser at 1064 nm to reduce background noise. Gold nanorods...

  • Biomedical Optics (BIOMED) 2012 paper: BM2B.8
  • OSA Technical Digest
  • Hu, Song; Maslov, Konstantin; Yan, Ping; Lee, Jin-Moo; Wang, Lihong V
  • We developed dichroism photoacoustic microscopy capable of imaging polarization-dependent optical absorption with excellent specificity. This innovation enriches photoacoustic...

  • Biomedical Optics (BIOMED) 2012 paper: BM4A.1
  • OSA Technical Digest
  • Spinelli, Lorenzo; Torricelli, Alessandro; Contini, Davide; Caffini, Matteo; Zucchelli, Lucia; Cubeddu, Rinaldo; Molteni, Erika; Bianchi, Anna Maria; Baselli, Giuseppe; Cerutti, Sergio; Visani, Elisa; Gilioli, Isabella; Rossi Sebastiano, Davide; Schiaffi, Elena; Panzica, Ferruccio; Franceschetti, Silvana
  • A multimodality fNIRS-EEG, fMRI-EEG and TMS clinical study was performed on adult volunteers and epileptic patients with movement disorders to assess cortical response during motor...

  • Biomedical Optics (BIOMED) 2012 paper: BM4A.2
  • OSA Technical Digest
  • Pouliot, Philippe; Truong Van, Tri; Zhang, Cong; Dubeau, Simon; Nguyen, Dang Khoa; Lesage, Frédéric
  • The hemodynamic responses to 4-AP induced focal epileptic spikes and electrical stimulations are compared in a rat model. Nonlinearities are quantified with biophysical models....

  • Biomedical Optics (BIOMED) 2012 paper: BM4A.3
  • OSA Technical Digest
  • Krüger, Arne; Koch, Stefan P; Mehnert, Jan; Habermehl, Christina; Piper, Sophie; Steinbrink, Jens; Obrig, Hellmuth; Schmitz, Christoph H
  • We present a miniaturized multi-channel NIRS imaging system for functional brain imaging in unrestrained settings suitable for any aspect of the head. Performance is demonstrated in a...

  • Biomedical Optics (BIOMED) 2012 paper: BM4A.4
  • OSA Technical Digest
  • Schei, Jennifer L; Cahall, Joseph E; Belenky, Gregory; Rector, David M
  • Evoked hemodynamic responses measured following sleep deprivation were larger compared baseline and recovery sleep nights. Attention differences during sleep deprivation showed larger...
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