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  • July 2009

Optics InfoBase > Spotlight on Optics > Surface-enhanced Raman scattering biosensor for DNA detection on nanoparticle island substrates


Surface-enhanced Raman scattering biosensor for DNA detection on nanoparticle island substrates

Published in Applied Optics, Vol. 48 Issue 22, pp.4329-4337 (2009)
by Wu Yuan, Ho Pui Ho, Rebecca K. Y. Lee, and Siu Kai Kong

Source article Abstract | Full Text: XHTML | Full Text: PDF


Spotlight summary: Surface-enhanced Raman scattering (SERS) is a leading strategy to achieve high sensitivity for gene detection and identification. However, the acceptance of SERS as a general analytical tool has been hindered somewhat by the lack of systematic development of substrate technology. This work presents a study on the SERS properties of novel engineered silver nanoparticle island substrates and their applications for target oligonucleotide detection.

Technical Division: Optics in Biology and Medicine
ToC Category: Medical Optics and Biotechnology
OCIS Codes: (170.5660) Medical optics and biotechnology : Raman spectroscopy
(240.6680) Optics at surfaces : Surface plasmons
(300.6450) Spectroscopy : Spectroscopy, Raman
(240.6695) Optics at surfaces : Surface-enhanced Raman scattering


Posted on July 23, 2009

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