Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Multispectral diffuse optical tomography with absorption and scattering spectral constraints

Not Accessible

Your library or personal account may give you access

Abstract

We present a new method to simultaneously reconstruct the images of oxyhemoglobin, deoxyhemoglobin, and water concentrations, as well as the volume fraction images of the scattering particles using continuous wave multispectral diffuse optical tomography with the absorption and scattering spectral prior constraints. In this method, the nonlinear relationship between the reduced scattering coefficient and the volume fraction and the size of the particles is linearized, allowing direct reconstruction of the volume fraction of scattering particles in tissues. The method is validated by a series of numerical simulations, phantom experiments, and in vivo clinical experiments. The initial clinical results indicate that the volume fraction of scattering particles in a malignant tumor is higher than that in a benign tumor.

© 2007 Optical Society of America

Full Article  |  PDF Article
More Like This
Diffuse optical tomography with spectral constraints and wavelength optimization

Alper Corlu, Regine Choe, Turgut Durduran, Kijoon Lee, Martin Schweiger, Simon R. Arridge, Elizabeth M. C. Hillman, and Arjun G. Yodh
Appl. Opt. 44(11) 2082-2093 (2005)

Spectrally constrained chromophore and scattering near-infrared tomography provides quantitative and robust reconstruction

Subhadra Srinivasan, Brian W. Pogue, Shudong Jiang, Hamid Dehghani, and Keith D. Paulsen
Appl. Opt. 44(10) 1858-1869 (2005)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (5)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Tables (2)

You do not have subscription access to this journal. Article tables are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Equations (11)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved