OSA's Digital Library

Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 3, Iss. 6 — Jun. 17, 2008

Adjoint time domain method for fluorescent imaging in turbid media

Vadim Y. Soloviev, Cosimo D’Andrea, Marco Brambilla, Gianluca Valentini, Ralf B. Schulz, Rinaldo Cubeddu, and Simon R. Arridge  »View Author Affiliations


Applied Optics, Vol. 47, Issue 13, pp. 2303-2311 (2008)
http://dx.doi.org/10.1364/AO.47.002303


View Full Text Article

Enhanced HTML    Acrobat PDF (5350 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

Application of adjoint time domain methods to the inverse problem in 3D fluorescence imaging is a novel approach. We demonstrate the feasibility of this approach experimentally on the basis of a time gating technique completely in the time domain by using a small number of time windows. The evolution of the fluorescence energy density function inside a highly scattering cylinder was reconstructed together with optical parameters. Reconstructed energy density was used in localizing two fluorescent tubes. Relatively accurate reconstruction demonstrates the effectiveness and the potential of the proposed technique.

© 2008 Optical Society of America

OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(290.0290) Scattering : Scattering
(290.7050) Scattering : Turbid media

ToC Category:
Scattering

History
Original Manuscript: October 25, 2007
Revised Manuscript: February 5, 2008
Manuscript Accepted: March 27, 2008
Published: April 28, 2008

Virtual Issues
Vol. 3, Iss. 6 Virtual Journal for Biomedical Optics

Citation
Vadim Y. Soloviev, Cosimo D'Andrea, Marco Brambilla, Gianluca Valentini, Ralf B. Schulz, Rinaldo Cubeddu, and Simon R. Arridge, "Adjoint time domain method for fluorescent imaging in turbid media," Appl. Opt. 47, 2303-2311 (2008)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-47-13-2303

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Log in to access OSA Member Subscription

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited