Adjoint time domain method for fluorescent imaging in turbid media
Applied Optics, Vol. 47, Issue 13, pp. 2303-2311 (2008)
http://dx.doi.org/10.1364/AO.47.002303
Enhanced HTML 
Acrobat PDF (5350 KB)
Abstract
Application of adjoint time domain methods to the inverse problem in 3D fluorescence imaging is a novel approach. We demonstrate the feasibility of this approach experimentally on the basis of a time gating technique completely in the time domain by using a small number of time windows. The evolution of the fluorescence energy density function inside a highly scattering cylinder was reconstructed together with optical parameters. Reconstructed energy density was used in localizing two fluorescent tubes. Relatively accurate reconstruction demonstrates the effectiveness and the potential of the proposed technique.
© 2008 Optical Society of America
OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(290.0290) Scattering : Scattering
(290.7050) Scattering : Turbid media
ToC Category:
Scattering
History
Original Manuscript: October 25, 2007
Revised Manuscript: February 5, 2008
Manuscript Accepted: March 27, 2008
Published: April 28, 2008
Virtual Issues
Vol. 3, Iss. 6 Virtual Journal for Biomedical Optics
Citation
Vadim Y. Soloviev, Cosimo D'Andrea, Marco Brambilla, Gianluca Valentini, Ralf B. Schulz, Rinaldo Cubeddu, and Simon R. Arridge, "Adjoint time domain method for fluorescent imaging in turbid media," Appl. Opt. 47, 2303-2311 (2008)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-47-13-2303
You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
Related Journal Articles 
- Phosphorescence Lifetime Imaging in Turbid Media: The Forward Problem (AO)
- Phosphorescence Lifetime Imaging in Turbid Media: The Inverse Problem and Experimental Image Reconstruction (AO)
- Feasibility of diffuse optical imaging with long-lived luminescent probes (OL)
- Dynamically adaptive mesh refinement technique for image reconstruction in optical tomography (AO)
- Consideration of a spread-out source in problems of near-infrared optical tomography (AO)
Related Conference Papers
- Image Reconstruction in Optical Tomography: Beyond the Diffusion Approximation
- Impulse-Response Reconstruction of a Scattering Medium with the Kramers-Kronig Method
- 3-D Fluorescence Imaging in Turbid Media by Using Time Gated Data Acquisition
- Simulated and experimental separation and characterization of absorptive inhomogeneities embedded in turbid media
- Förster Resonance Energy Transfer Reconstruction from Optical Backprojections in Turbid Media
« Previous Article | Next Article »
OSA is a member of 