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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 4, Iss. 9 — Sep. 4, 2009

Effect of contact force on breast tissue optical property measurements using a broadband diffuse optical spectroscopy handheld probe

Albert Cerussi, Sarah Siavoshi, Amanda Durkin, Cynthia Chen, Wendy Tanamai, David Hsiang, and Bruce J. Tromberg  »View Author Affiliations


Applied Optics, Vol. 48, Issue 21, pp. 4270-4277 (2009)
http://dx.doi.org/10.1364/AO.48.004270


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Abstract

We investigated the effects of operator-applied force on diffuse optical spectroscopy (DOS) by integrating a force transducer into the handheld probe. Over the typical range of contact forces measured in the breasts of eight patients, absorption and reduced scattering coefficients (650 to 1000 nm ) variance was 3.1 ± 1.0 % and 1.0 ± 0.4 % . For trained operators, we observed < 5 % variation in hemoglobin and < 2 % variation in water and lipids. Contact force is not a significant source of variation, most likely because of a relatively wide probe surface area and the stability of the DOS method for calculating tissue optical properties.

© 2009 Optical Society of America

OCIS Codes
(120.3890) Instrumentation, measurement, and metrology : Medical optics instrumentation
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.5280) Medical optics and biotechnology : Photon migration
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics
(170.6935) Medical optics and biotechnology : Tissue characterization

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: October 10, 2008
Revised Manuscript: April 2, 2009
Manuscript Accepted: May 13, 2009
Published: July 17, 2009

Virtual Issues
Vol. 4, Iss. 9 Virtual Journal for Biomedical Optics

Citation
Albert Cerussi, Sarah Siavoshi, Amanda Durkin, Cynthia Chen, Wendy Tanamai, David Hsiang, and Bruce J. Tromberg, "Effect of contact force on breast tissue optical property measurements using a broadband diffuse optical spectroscopy handheld probe," Appl. Opt. 48, 4270-4277 (2009)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-48-21-4270


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