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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editor: Gregory W. Faris
  • Vol. 5, Iss. 10 — Jul. 19, 2010

Direct-current-based image reconstruction versus direct-current included or excluded frequency-domain reconstruction in diffuse optical tomography

Guan Xu, Daqing Piao, Charles F. Bunting, and Hamid Dehghani  »View Author Affiliations

Applied Optics, Vol. 49, Issue 16, pp. 3059-3070 (2010)

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We study the level of image artifacts in optical tomography associated with measurement uncertainty under three reconstruction configurations, namely, by using only direct-current (DC), DC-excluded frequency-domain, and DC-included frequency-domain data. Analytic and synthetic studies demonstrate that, at the same level of measurement uncertainty typical to optical tomography, the ratio of the standard deviation of μ a over μ a reconstructed by DC only is at least 1.4 times lower than that by frequency-domain methods. The ratio of standard deviations of D (or μ s ) over D (or μ s ) reconstructed by DC only are slightly lower than those by frequency-domain methods. Frequency-domain reconstruction including DC generally outperforms that excluding DC, but as the amount of measurements increases, the difference between the two diminishes. Under the condition of a priori structural information, the performances of three reconstruction configurations are seemingly equivalent.

© 2010 Optical Society of America

OCIS Codes
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5270) Medical optics and biotechnology : Photon density waves
(170.6960) Medical optics and biotechnology : Tomography

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: September 25, 2009
Revised Manuscript: March 16, 2010
Manuscript Accepted: March 29, 2010
Published: May 25, 2010

Virtual Issues
Vol. 5, Iss. 10 Virtual Journal for Biomedical Optics

Guan Xu, Daqing Piao, Charles F. Bunting, and Hamid Dehghani, "Direct-current-based image reconstruction versus direct-current included or excluded frequency-domain reconstruction in diffuse optical tomography," Appl. Opt. 49, 3059-3070 (2010)

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