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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 7, Iss. 9 — Aug. 28, 2012

Microfluidic sorting with a moving array of optical traps

Raktim Dasgupta, Sunita Ahlawat, and Pradeep Kumar Gupta  »View Author Affiliations


Applied Optics, Vol. 51, Issue 19, pp. 4377-4387 (2012)
http://dx.doi.org/10.1364/AO.51.004377


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Abstract

Optical sorting was demonstrated by selective trapping of a set of microspheres (having specific size or composition) from a flowing mixture and guiding these in the desired direction by a moving array of optical traps. The approach exploits the fact that whereas the fluid drag force varies linearly with particle size, the optical gradient force has a more complex dependence on the particle size and also on its optical properties. Therefore, the ratio of these two forces is unique for different types of flowing particles. Selective trapping of a particular type of particles can thus be achieved by ensuring that the ratio between fluid drag and optical gradient force on these is below unity whereas for others it exceeds unity. Thereafter, the trapped particles can be sorted using a motion of the trapping sites towards the output. Because in this method the trapping force seen by the selected fraction of particles can be suitably higher than the fluid drag force, the particles can be captured and sorted from a fast fluid flow (about 150μm/s). Therefore, even when using a dilute particle suspension, where the colloidal trafficking issues are naturally minimized, due to high flow rate a good throughput (about 30particles/s) can be obtained. Experiments were performed to demonstrate sorting between silica spheres of different sizes (2, 3, and 5 μm) and between 3 μm size silica and polystyrene spheres.

© 2012 Optical Society of America

OCIS Codes
(110.0180) Imaging systems : Microscopy
(350.4855) Other areas of optics : Optical tweezers or optical manipulation

ToC Category:
Optical Tweezers or Optical Manipulation

History
Original Manuscript: February 27, 2012
Revised Manuscript: May 18, 2012
Manuscript Accepted: May 22, 2012
Published: June 26, 2012

Virtual Issues
Vol. 7, Iss. 9 Virtual Journal for Biomedical Optics

Citation
Raktim Dasgupta, Sunita Ahlawat, and Pradeep Kumar Gupta, "Microfluidic sorting with a moving array of optical traps," Appl. Opt. 51, 4377-4387 (2012)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-51-19-4377

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