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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 6, Iss. 1 — Jan. 3, 2011

Time-Resolved Diffuse Optical Spectroscopy: A Differential Absorption Approach

Paola Taroni, Andrea Bassi, Lorenzo Spinelli, Rinaldo Cubeddu, and Antonio Pifferi

Applied Spectroscopy, Vol. 64, Issue 11, pp. 1220-1226 (2010)


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Abstract

A method is presented for the estimate of spectral changes in the absorption properties of turbid media from time-resolved diffuse optical spectroscopy. The method relies on the hypothesis of constant scattering over the wavelength range of interest, but no limitations come from the sample size and shape as the method is derived directly from the Beer–Lambert law. The effects of a moderate spectral dependence of the scattering properties and of the non-ideal instrument response function were investigated theoretically, and the results were confirmed experimentally, showing that the method can be profitably applied in cases of practical interest.

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Vol. 6, Iss. 1 Virtual Journal for Biomedical Optics

Citation
Paola Taroni, Andrea Bassi, Lorenzo Spinelli, Rinaldo Cubeddu, and Antonio Pifferi, "Time-Resolved Diffuse Optical Spectroscopy: A Differential Absorption Approach," Appl. Spectrosc. 64, 1220-1226 (2010)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=as-64-11-1220


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