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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 3, Iss. 6 — Jun. 17, 2008

Assessment of arterial characteristics in human atherosclerosis by extracting optical properties from polarization-sensitive optical coherence tomography

Wen-Chuan Kuo, Ming-Wei Hsiung, Jeou-Jong Shyu, Nai-Kuan Chou, and Po-Nien Yang  »View Author Affiliations


Optics Express, Vol. 16, Issue 11, pp. 8117-8125 (2008)
http://dx.doi.org/10.1364/OE.16.008117


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Abstract

In this research, we assessed arterial characteristics in human atherosclerosis by determining both scattering and birefringence properties of vessel tissue from polarization-sensitive optical coherence tomography (PS-OCT) images. We demonstrated that optical characteristics including scattering coefficient (µs), effective anisotropy factor (g eff ), birefringence coefficient (Δn), and fast-axis angle (Β) of normal and different kinds of atherosclerotic lesions in human vessels can be quantitatively described. Based on our findings, a quantitative PS-OCT image criterion for plaque characterization was constructed.

© 2008 Optical Society of America

OCIS Codes
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.4580) Medical optics and biotechnology : Optical diagnostics for medicine
(260.5430) Physical optics : Polarization

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: March 20, 2008
Revised Manuscript: May 17, 2008
Manuscript Accepted: May 17, 2008
Published: May 20, 2008

Virtual Issues
Vol. 3, Iss. 6 Virtual Journal for Biomedical Optics

Citation
Wen-Chuan Kuo, Ming-Wei Hsiung, Jeou-Jong Shyu, Nai-Kuan Chou, and Po-Nien Yang, "Assessment of arterial characteristics in human atherosclerosis by extracting optical properties from polarization-sensitive optical coherence tomography," Opt. Express 16, 8117-8125 (2008)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-16-11-8117


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