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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 4, Iss. 5 — May. 5, 2009

Ultra-high-speed volumetric tomography of human retinal blood flow

Tilman Schmoll, Christoph Kolbitsch, and Rainer A. Leitgeb  »View Author Affiliations


Optics Express, Vol. 17, Issue 5, pp. 4166-4176 (2009)
http://dx.doi.org/10.1364/OE.17.004166


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Abstract

Applying novel detector development based on CMOS technology to Fourier domain optical coherence tomography we achieve depth profile rates up to 200,000 scans/sec. This speed allows for dramatic improvement for imaging small retinal details, such as photo-receptors and capillaries. We demonstrate the impact of this achievable speed to Doppler tomography and discuss advantages as well as short-comings of high speed 3D Doppler imaging of the human retina. Experimental data of 3D static D-FDOCT sets from fovea and nerve head region are shown together with first 4D imaging of retinal capillary flow.

© 2009 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.2655) Medical optics and biotechnology : Functional monitoring and imaging

ToC Category:
Functional OCT

History
Original Manuscript: November 19, 2008
Revised Manuscript: February 4, 2009
Manuscript Accepted: February 19, 2009
Published: March 2, 2009

Virtual Issues
Vol. 4, Iss. 5 Virtual Journal for Biomedical Optics
Interactive Science Publishing Focus Issue: Optical Coherence Tomography (OCT) (2009) Optics Express

Citation
Tilman Schmoll, Christoph Kolbitsch, and Rainer A. Leitgeb, "Ultra-high-speed volumetric tomography of human retinal blood flow," Opt. Express 17, 4166-4176 (2009)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-17-5-4166


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