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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 5, Iss. 14 — Nov. 16, 2010

Automated layer segmentation of macular OCT images using dual-scale gradient information

Qi Yang, Charles A. Reisman, Zhenguo Wang, Yasufumi Fukuma, Masanori Hangai, Nagahisa Yoshimura, Atsuo Tomidokoro, Makoto Araie, Ali S. Raza, Donald C. Hood, and Kinpui Chan  »View Author Affiliations


Optics Express, Vol. 18, Issue 20, pp. 21293-21307 (2010)
http://dx.doi.org/10.1364/OE.18.021293


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Abstract

A novel automated boundary segmentation algorithm is proposed for fast and reliable quantification of nine intra-retinal boundaries in optical coherence tomography (OCT) images. The algorithm employs a two-step segmentation schema based on gradient information in dual scales, utilizing local and complementary global gradient information simultaneously. A shortest path search is applied to optimize the edge selection. The segmentation algorithm was validated with independent manual segmentation and a reproducibility study. It demonstrates high accuracy and reproducibility in segmenting normal 3D OCT volumes. The execution time is about 16 seconds per volume (480x512x128 voxels). The algorithm shows potential for quantifying images from diseased retinas as well.

© 2010 OSA

OCIS Codes
(100.0100) Image processing : Image processing
(170.4470) Medical optics and biotechnology : Ophthalmology
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: August 12, 2010
Revised Manuscript: September 9, 2010
Manuscript Accepted: September 13, 2010
Published: September 22, 2010

Virtual Issues
Vol. 5, Iss. 14 Virtual Journal for Biomedical Optics

Citation
Qi Yang, Charles A. Reisman, Zhenguo Wang, Yasufumi Fukuma, Masanori Hangai, Nagahisa Yoshimura, Atsuo Tomidokoro, Makoto Araie, Ali S. Raza, Donald C. Hood, and Kinpui Chan, "Automated layer segmentation of macular OCT images using dual-scale gradient information," Opt. Express 18, 21293-21307 (2010)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-18-20-21293


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