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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 7, Iss. 2 — Feb. 1, 2012

Automatic montage of SD-OCT data sets

Ying Li, Giovanni Gregori, Byron L. Lam, and Philip J. Rosenfeld  »View Author Affiliations


Optics Express, Vol. 19, Issue 27, pp. 26239-26248 (2011)
http://dx.doi.org/10.1364/OE.19.026239


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Abstract

This paper proposes an automatic algorithm for the montage of OCT data sets, which produces a composite 3D OCT image over a large field of view out of several separate, partially overlapping OCT data sets. First the OCT fundus images (OFIs) are registered, using blood vessel ridges as the feature of interest and a two step iterative procedure to minimize the distance between all matching point pairs over the set of OFIs. Then the OCT data sets are merged to form a full 3D montage using cross-correlation. The algorithm was tested using an imaging protocol consisting of 8 OCT images for each eye, overlapping to cover a total retinal region of approximately 50x35 degrees. The results for 3 normal eyes and 3 eyes with retinal degeneration are analyzed, showing registration errors of 1.5±0.3 and 2.0±0.8 pixels respectively.

© 2011 OSA

OCIS Codes
(100.0100) Image processing : Image processing
(110.4500) Imaging systems : Optical coherence tomography
(170.4460) Medical optics and biotechnology : Ophthalmic optics and devices
(170.5755) Medical optics and biotechnology : Retina scanning

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: September 19, 2011
Revised Manuscript: November 17, 2011
Manuscript Accepted: November 20, 2011
Published: December 8, 2011

Virtual Issues
Vol. 7, Iss. 2 Virtual Journal for Biomedical Optics

Citation
Ying Li, Giovanni Gregori, Byron L. Lam, and Philip J. Rosenfeld, "Automatic montage of SD-OCT data sets," Opt. Express 19, 26239-26248 (2011)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-19-27-26239


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