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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 7, Iss. 11 — Oct. 31, 2012

A new design of light illumination scheme for deep tissue photoacoustic imaging

Zhaohui Wang, Seunghan Ha, and Kang Kim  »View Author Affiliations


Optics Express, Vol. 20, Issue 20, pp. 22649-22659 (2012)
http://dx.doi.org/10.1364/OE.20.022649


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Abstract

A new light illumination scheme to increase imaging depth in photoacoustic (PA) imaging was designed and evaluated by in silico simulations and tested by in vitro experiments. A relatively large portion of the light energy shining into the body of a human reflects off the skin surfaces. Collecting the reflected light and redirecting it onto skin surfaces will increase the effective input energy, resulting in an increase of light penetration depth for the same light source. Its performance in PA imaging was evaluated using a finite element (FE)-based numerical simulation model composed of four modules. In the in vitro experiments with the light catcher, PA image of multiple targets at different locations exhibited an enhancement both in uniformity and in depth of the light illumination.

© 2012 OSA

OCIS Codes
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.5120) Medical optics and biotechnology : Photoacoustic imaging

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: June 6, 2012
Revised Manuscript: August 29, 2012
Manuscript Accepted: September 11, 2012
Published: September 19, 2012

Virtual Issues
Vol. 7, Iss. 11 Virtual Journal for Biomedical Optics

Citation
Zhaohui Wang, Seunghan Ha, and Kang Kim, "A new design of light illumination scheme for deep tissue photoacoustic imaging," Opt. Express 20, 22649-22659 (2012)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-20-20-22649


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