Adaptive optical probe design for optical coherence tomography and microscopy using tunable optics

doi:10.1364/OE.21.001567

Adaptive optical probe design for optical coherence tomography and microscopy using tunable optics

Minseog Choi, Seungwan Lee, Jong-hyeon Chang, Eunsung Lee, Kyu-Dong Jung, and Woonbae Kim »View Author Affiliations

Optics Express, Vol. 21, Issue 2, pp. 1567-1573 (2013)
http://dx.doi.org/10.1364/OE.21.001567

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Abstract
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References (13)
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Abstract

We present a tunable, adaptive optical imaging probe for multimodal imaging such as optical coherence tomography and microscopy. The probe is compatible with forward-looking scanning laser imaging devices such as an endoscope. The lens configuration includes a tunable iris and two varifocal lenses, both driven by microelectrofluidics, as well as several conventional fixed focus lenses. The modulation transfer function and spot size in the focal plane is evaluated, and we show using optical simulations that there are three possible imaging modes with different transverse resolutions and focal depths.

OCIS Codes
(170.2150) Medical optics and biotechnology : Endoscopic imaging
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.3890) Medical optics and biotechnology : Medical optics instrumentation

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: October 16, 2012
Revised Manuscript: December 17, 2012
Manuscript Accepted: January 2, 2013
Published: January 15, 2013

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Vol. 8, Iss. 2 Virtual Journal for Biomedical Optics

Citation
Minseog Choi, Seungwan Lee, Jong-hyeon Chang, Eunsung Lee, Kyu-Dong Jung, and Woonbae Kim, "Adaptive optical probe design for optical coherence tomography and microscopy using tunable optics," Opt. Express 21, 1567-1573 (2013)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-21-2-1567

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References

J. M. Schmitt, “Optical coherence tomography (OCT): a review,” IEEE J. Sel. Top. Quantum Electron.5(4), 1205–1215 (1999). [CrossRef]
J. G. Fujimoto, “Optical coherence tomography,” C. R. Acad. Sci. Paris Ser. IV2, 1099–1111 (2001).
P. H. Tomlins and R. K. Wang, “Theory, developments and applications of optical coherence tomography,” J. Phys. D Appl. Phys.38(15), 2519–2535 (2005). [CrossRef]
Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, “Methods and application areas of endoscopic optical coherence tomography,” J. Biomed. Opt.11(6), 063001 (2006). [CrossRef] [PubMed]
J. A. Evans and N. S. Nishioka, “Endoscopic confocal microscopy,” Curr. Opin. Gastroenterol.21(5), 578–584 (2005). [CrossRef] [PubMed]
C. Liang, K. B. Sung, R. R. Richards-Kortum, and M. R. Descour, “Design of a high-numerical-aperture miniature microscope objective for an endoscopic fiber confocal reflectance microscope,” Appl. Opt.41(22), 4603–4610 (2002). [CrossRef] [PubMed]
R. T. Kester, T. S. Tkaczyk, M. R. Descour, T. Christenson, and R. R. Richards-Kortum, “High numerical aperture microendoscope objective for a fiber confocal reflectance microscope,” Opt. Express15(5), 2409–2420 (2007). [CrossRef] [PubMed]
B. Qi, A. P. Himmer, L. M. Gordon, X. D. V. Yang, L. D. Dickensheets, and I. A. Vitkin, “Dynamic focus control in high-speed optical coherence tomography based on a microelectromechanical mirror,” Opt. Commun.232(1-6), 123–128 (2004). [CrossRef]
A. Divetia, T. H. Hsieh, J. Zhang, Z. Chen, M. Bachman, and G. P. Li, “Dynamically focused optical coherence tomography for endoscopic applications,” Appl. Phys. Lett.86(10), 103902 (2005). [CrossRef]
K. Aljasem, A. Werber, A. Seifert, and H. Zappe, “Fiber optic tunable probe for endoscopic optical coherence tomography,” J. Opt. A, Pure Appl. Opt.10(4), 044012 (2008). [CrossRef]
J. P. Rolland, S. Murali, P. Meemon, P. Glenn, K. P. Thompson, and K.-S. Lee, “Performance of a Liquid lens enabled optical coherence microscope with Gabor fusion,” in International Optical Design Conference, Technical Digest (CD) (Optical Society of America, 2010), paper IWD4.
J.-H. Chang, K.-D. Jung, E. Lee, M. Choi, and S. Lee, “Microelectrofluidic iris for variable aperture,” Proc. SPIE8252, 82520O, 82520O–6 (2012). [CrossRef]
J.-H. Chang, K.-D. Jung, E. Lee, M. Choi, S. Lee, and W. Kim, “Varifocal liquid lens based on microelectrofluidic technology,” Opt. Lett.37(21), 4377–4379 (2012). [CrossRef] [PubMed]

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[1] J. M. Schmitt, “Optical coherence tomography (OCT): a review,” IEEE J. Sel. Top. Quantum Electron.5(4), 1205–1215 (1999). [CrossRef]

[2] J. G. Fujimoto, “Optical coherence tomography,” C. R. Acad. Sci. Paris Ser. IV2, 1099–1111 (2001).

[3] P. H. Tomlins and R. K. Wang, “Theory, developments and applications of optical coherence tomography,” J. Phys. D Appl. Phys.38(15), 2519–2535 (2005). [CrossRef]

[4] Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, “Methods and application areas of endoscopic optical coherence tomography,” J. Biomed. Opt.11(6), 063001 (2006). [CrossRef] [PubMed]

[5] J. A. Evans and N. S. Nishioka, “Endoscopic confocal microscopy,” Curr. Opin. Gastroenterol.21(5), 578–584 (2005). [CrossRef] [PubMed]

[6] C. Liang, K. B. Sung, R. R. Richards-Kortum, and M. R. Descour, “Design of a high-numerical-aperture miniature microscope objective for an endoscopic fiber confocal reflectance microscope,” Appl. Opt.41(22), 4603–4610 (2002). [CrossRef] [PubMed]

[7] R. T. Kester, T. S. Tkaczyk, M. R. Descour, T. Christenson, and R. R. Richards-Kortum, “High numerical aperture microendoscope objective for a fiber confocal reflectance microscope,” Opt. Express15(5), 2409–2420 (2007). [CrossRef] [PubMed]

[8] B. Qi, A. P. Himmer, L. M. Gordon, X. D. V. Yang, L. D. Dickensheets, and I. A. Vitkin, “Dynamic focus control in high-speed optical coherence tomography based on a microelectromechanical mirror,” Opt. Commun.232(1-6), 123–128 (2004). [CrossRef]

[9] A. Divetia, T. H. Hsieh, J. Zhang, Z. Chen, M. Bachman, and G. P. Li, “Dynamically focused optical coherence tomography for endoscopic applications,” Appl. Phys. Lett.86(10), 103902 (2005). [CrossRef]

[10] K. Aljasem, A. Werber, A. Seifert, and H. Zappe, “Fiber optic tunable probe for endoscopic optical coherence tomography,” J. Opt. A, Pure Appl. Opt.10(4), 044012 (2008). [CrossRef]

[11] J. P. Rolland, S. Murali, P. Meemon, P. Glenn, K. P. Thompson, and K.-S. Lee, “Performance of a Liquid lens enabled optical coherence microscope with Gabor fusion,” in International Optical Design Conference, Technical Digest (CD) (Optical Society of America, 2010), paper IWD4.

[12] J.-H. Chang, K.-D. Jung, E. Lee, M. Choi, and S. Lee, “Microelectrofluidic iris for variable aperture,” Proc. SPIE8252, 82520O, 82520O–6 (2012). [CrossRef]

[13] J.-H. Chang, K.-D. Jung, E. Lee, M. Choi, S. Lee, and W. Kim, “Varifocal liquid lens based on microelectrofluidic technology,” Opt. Lett.37(21), 4377–4379 (2012). [CrossRef] [PubMed]

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Adaptive optical probe design for optical coherence tomography and microscopy using tunable optics