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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editor: Gregory W. Faris
  • Vol. 2, Iss. 10 — Oct. 31, 2007

Tomographic imaging of absolute optical absorption coefficient in turbid media using combined photoacoustic and diffusing light measurements

Lu Yin, Qiang Wang, Qizhi Zhang, and Huabei Jiang  »View Author Affiliations

Optics Letters, Vol. 32, Issue 17, pp. 2556-2558 (2007)

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We present a new method that can provide high resolution images of absolute optical absorption coefficient in heterogeneous turbid media. In this method, acoustic measurements in conventional photoacoustic tomography are combined with diffusing light measurements to separate the product of absorption coefficient and optical fluence or photon density. We validate this method using a series of tissuelike phantom experiments. The experimental results show that targets as small as 0.5 mm in diameter with optical absorption contrasts as low as 1.5 relative to a 50 mm diameter scattering background medium can be clearly detected.

© 2007 Optical Society of America

OCIS Codes
(110.5120) Imaging systems : Photoacoustic imaging
(110.6960) Imaging systems : Tomography
(110.7050) Imaging systems : Turbid media
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(110.6955) Imaging systems : Tomographic imaging

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: February 2, 2007
Revised Manuscript: June 15, 2007
Manuscript Accepted: July 6, 2007
Published: August 21, 2007

Virtual Issues
Vol. 2, Iss. 10 Virtual Journal for Biomedical Optics

Lu Yin, Qiang Wang, Qizhi Zhang, and Huabei Jiang, "Tomographic imaging of absolute optical absorption coefficient in turbid media using combined photoacoustic and diffusing light measurements," Opt. Lett. 32, 2556-2558 (2007)

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  1. G. Paltauf, J. Viator, S. Prahl, and S. Jacques, J. Acoust. Soc. Am. 112, 1536 (2002). [CrossRef] [PubMed]
  2. S. J. Norton and T. Vo-Dinh, J. Opt. Soc. Am. A 20, 1859 (2003). [CrossRef]
  3. A. A. Oraevsky, A. A. Karabutov, V. S. Solomatin, E. V. Savateeva, V. G. Andreev, and Z. Gatalica, Proc. SPIE 4256, 12 (2001).
  4. R. A. Kruger, D. Reinecke, and G. Kruger, Med. Phys. 26, 1832 (1999). [CrossRef] [PubMed]
  5. C. G. A. Hoelen, F. F. M. de Mul, R. Pongers, and A. Dekker, Opt. Lett. 23, 648 (1998). [CrossRef]
  6. J. Laufer, D. Delpy, C. Elwell, and P. Beard, Phys. Med. Biol. 52, 141 (2007). [CrossRef]
  7. B. Cox, S. Arridge, K. Kostli, and P. Beard, Proc. SPIE 5697, 49 (2005). [CrossRef]
  8. Z. Yuan and H. Jiang, Appl. Phys. Lett. 88, 231101 (2006). [CrossRef]
  9. Z. Yuan, C. Wu, H. Zhao, and H. Jiang, Opt. Lett. 30, 3054 (2005). [CrossRef] [PubMed]
  10. H. Jiang, Y. Xu, and N. Iftimia, Opt. Express 7, 204 (2000). [CrossRef] [PubMed]

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