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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 5, Iss. 2 — Jan. 21, 2010

Label-free photoacoustic ophthalmic angiography

Song Hu, Bin Rao, Konstantin Maslov, and Lihong V. Wang  »View Author Affiliations


Optics Letters, Vol. 35, Issue 1, pp. 1-3 (2010)
http://dx.doi.org/10.1364/OL.35.000001


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Abstract

We present label-free functional photoacoustic imaging of the ocular microvasculature in living animals. The anterior segment of an adult mouse was imaged with a laser exposure level well within the American National Standards Institute safety standards. Individual red blood cells traveling along the iris capillaries were clearly resolved, and the hemoglobin oxygen saturation in the iris microvasculature was imaged spectrally. We believe that photoacoustic imaging has the potential to advance the diagnosis and treatment of ocular diseases in humans.

© 2009 Optical Society of America

OCIS Codes
(140.3360) Lasers and laser optics : Laser safety and eye protection
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5120) Medical optics and biotechnology : Photoacoustic imaging
(330.7327) Vision, color, and visual optics : Visual optics, ophthalmic instrumentation

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: September 10, 2009
Revised Manuscript: November 15, 2009
Manuscript Accepted: November 16, 2009
Published: December 17, 2009

Virtual Issues
Vol. 5, Iss. 2 Virtual Journal for Biomedical Optics

Citation
Song Hu, Bin Rao, Konstantin Maslov, and Lihong V. Wang, "Label-free photoacoustic ophthalmic angiography," Opt. Lett. 35, 1-3 (2010)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-35-1-1

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Supplementary Material


» Media 1: MOV (2800 KB)     

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