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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 5, Iss. 2 — Jan. 21, 2010

High-resolution computed tomography of refractive index distribution by transillumination low-coherence interferometry

Yi Wang and Ruikang K. Wang  »View Author Affiliations


Optics Letters, Vol. 35, Issue 1, pp. 91-93 (2010)
http://dx.doi.org/10.1364/OL.35.000091


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Abstract

We present a method to image refractive index distribution within a sample across 8 mm dimension with high spatial resolution by a transmission low-coherence interferometer. The relative strong forward-scattering light is collected, from which the parallel projections of refractive indices within the sample are obtained. A convolution backprojection algorithm is used to transform the projection data set recorded at sufficient angular views into the spatial distribution of refractive indices within the sample. We experimentally demonstrate this method by imaging a phantom. We show that this method can achieve a precision of 0.01 in determining the refractive index and a spatial resolution of 40 μ m .

© 2009 Optical Society of America

OCIS Codes
(170.3010) Medical optics and biotechnology : Image reconstruction techniques
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(290.3030) Scattering : Index measurements

ToC Category:
Imaging Systems

History
Original Manuscript: October 5, 2009
Revised Manuscript: November 27, 2009
Manuscript Accepted: December 1, 2009
Published: December 31, 2009

Virtual Issues
Vol. 5, Iss. 2 Virtual Journal for Biomedical Optics

Citation
Yi Wang and Ruikang K. Wang, "High-resolution computed tomography of refractive index distribution by transillumination low-coherence interferometry," Opt. Lett. 35, 91-93 (2010)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-35-1-91


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