OSA's Digital Library

Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 6, Iss. 1 — Jan. 3, 2011

Analysis of a diffusion-model-based approach for efficient quantification of superficial tissue properties

Sheng-Hao Tseng and Ming-Feng Hou  »View Author Affiliations


Optics Letters, Vol. 35, Issue 22, pp. 3739-3741 (2010)
http://dx.doi.org/10.1364/OL.35.003739


View Full Text Article

Enhanced HTML    Acrobat PDF (234 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

Previously, we reported using a diffusing probe in conjunction with a two-layer diffusion model for accurately recovering the optical properties of superficial volumes. However, the two-layer diffusion equation is computationally less efficient than a standard diffusion equation (SDE) by 3 orders of magnitude. In this Letter, we present a new approach extended from the diffusing probe geometry that enables the use of a diffusion model that has efficiency comparable to an SDE. Our Monte Carlo simulation results indicate that this new approach is not only very accurate but also sensitive to the presence of 0.5 mm 3 inhomogeneities and could be used for monitoring the early progression of skin melanoma.

© 2010 Optical Society of America

OCIS Codes
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.5270) Medical optics and biotechnology : Photon density waves
(170.2655) Medical optics and biotechnology : Functional monitoring and imaging

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: September 9, 2010
Manuscript Accepted: October 1, 2010
Published: November 3, 2010

Virtual Issues
Vol. 6, Iss. 1 Virtual Journal for Biomedical Optics

Citation
Sheng-Hao Tseng and Ming-Feng Hou, "Analysis of a diffusion-model-based approach for efficient quantification of superficial tissue properties," Opt. Lett. 35, 3739-3741 (2010)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-35-22-3739


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. D. A. Boas, M. A. O’Leary, B. Chance, and A. G. Yodh, Appl. Opt. 36, 75 (1997). [CrossRef] [PubMed]
  2. K. M. Yoo, F. Liu, and R. R. Alfano, Phys. Rev. Lett. 64, 2647 (1990). [CrossRef] [PubMed]
  3. Q. Liu and N. Ramanujam, J. Opt. Soc. Am. A 24, 1011(2007). [CrossRef]
  4. S. H. Tseng, C. Hayakawa, J. Spanier, and A. J. Durkin, J. Biomed. Opt. 14, 054043 (2009). [CrossRef] [PubMed]
  5. N. Kollias, Y. H. Malallah, H. AlAjmi, A. Baqer, B. E. Johnson, and S. Gonzalez, Photoderm. Photoimm. Photomed. 12, 183 (1996). [CrossRef]
  6. T. H. Pham, T. Spott, L. O. Svaasand, and B. J. Tromberg, Appl. Opt. 39, 4733 (2000). [CrossRef]
  7. A. Kienle, M. S. Patterson, N. Dognitz, R. Bays, G. Wagnieres, and H. van den Bergh, Appl. Opt. 37, 779 (1998). [CrossRef]
  8. L. H. Wang, S. L. Jacques, and L. Q. Zheng, Comput. Methods Programs Biomed. 47, 131 (1995). [CrossRef] [PubMed]
  9. C. M. Balch, S. J. Soong, J. E. Gershenwald, J. F. Thompson, D. S. Reintgen, N. Cascinelli, M. Urist, K. M. McMasters, M. I. Ross, J. M. Kirkwood, M. B. Atkins, J. A. Thompson, D. G. Coit, D. Byrd, R. Desmond, Y. Zhang, P. Y. Liu, G. H. Lyman, and A. Morabito, J. Clin. Oncol. 19, 3622 (2001). [PubMed]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

Figures

Fig. 1 Fig. 2 Fig. 3
 

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited