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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 7, Iss. 6 — May. 25, 2012

Multifocal multiphoton endoscope

David R. Rivera, Christopher M. Brown, Dimitre G. Ouzounov, Watt W. Webb, and Chris Xu  »View Author Affiliations


Optics Letters, Vol. 37, Issue 8, pp. 1349-1351 (2012)
http://dx.doi.org/10.1364/OL.37.001349


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Abstract

We report a miniaturized resonant/non-resonant multi-fiber raster scanner that is paired with a gradient-index lens assembly to achieve a compact and flexible multifocal multiphoton endoscope capable of longitudinal parallel image acquisition. Multiphoton images are obtained simultaneously at three axial depths, separated by 4.8μm, by incorporating three axially offset double clad optical fibers into the miniaturized scanner. The fabricated endoscope has an outer diameter of 3 mm, a rigid length of 4 cm, and acquires images at 4frames/s per focal plane, with lateral and axial resolutions for two-photon imaging of 0.8 and 10 μm, respectively.

© 2012 Optical Society of America

OCIS Codes
(110.2350) Imaging systems : Fiber optics imaging
(170.1610) Medical optics and biotechnology : Clinical applications
(170.2150) Medical optics and biotechnology : Endoscopic imaging

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: January 9, 2012
Revised Manuscript: February 13, 2012
Manuscript Accepted: February 27, 2012
Published: April 11, 2012

Virtual Issues
Vol. 7, Iss. 6 Virtual Journal for Biomedical Optics

Citation
David R. Rivera, Christopher M. Brown, Dimitre G. Ouzounov, Watt W. Webb, and Chris Xu, "Multifocal multiphoton endoscope," Opt. Lett. 37, 1349-1351 (2012)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-37-8-1349


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