Image correction scheme applied to functional diffuse optical tomography scattering images

Harry L. Graber; Yong Xu; Randall L. Barbour

doi:10.1364/AO.46.001705

Applied Optics
Vol. 46,
Issue 10,
pp. 1705-1716
(2007)
•https://doi.org/10.1364/AO.46.001705

Image correction scheme applied to functional diffuse optical tomography scattering images

Harry L. Graber, Yong Xu, and Randall L. Barbour

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Harry L. Graber, Yong Xu, and Randall L. Barbour, "Image correction scheme applied to functional diffuse optical tomography scattering images," Appl. Opt. 46, 1705-1716 (2007)

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Related Topics
Table of Contents Category
- Diffuse optical imaging
Optics & Photonics Topics
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The topics in this list come from the Optics and Photonics Topics applied to this article.

About this Article
History
- Original Manuscript: July 12, 2006
- Revised Manuscript: November 16, 2006
- Manuscript Accepted: November 27, 2006
- Published: March 13, 2007
Virtual Issues
Virtual Journal for Biomedical Optics Vol. 2, Iss. 5

Abstract

We have extended our investigation on the use of a linear algorithm for enhancing the accuracy of diffuse optical tomography (DOT) images, to include spatial maps of the diffusion coefficient. The results show that the corrected images are markedly improved in terms of estimated size, spatial resolution, two-object resolving power, and quantitative accuracy. These image-enhancing effects are significant at expected levels of diffusion-coefficient contrast in tissue and noise levels typical of experimental DOT data. Overall, the types and magnitudes of image-enhancing effects obtained here are qualitatively similar to those seen in previous studies on $μ_{a}$ perturbations. The implications for practical implementations of DOT time-series imaging are discussed.

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Number of Inclusions	Noise Level^a	SC^b		RM^c		RW^c
Number of Inclusions	Noise Level^a	Uncorrected	Corrected	Uncorrected	Corrected	Uncorrected	Corrected
1	0%	0.87	0.93	0.65	0.96	1.23	1.05
	1%	0.87	0.90	0.65	0.96	1.23	1.05
	2%	0.87	0.80	0.65	0.93	1.12	1.12
	3%	0.87	0.70	0.65	0.87	1.12	1.07
	5%	0.87	0.56	0.65	0.85	1.15	0.98
	8%	0.86	0.38	0.65	0.83	1.12	1.07
2	0%	0.43	0.65	0.14	0.49	–	1.46
	1%	0.43	0.62	0.14	0.48	–	1.46
	2%	0.43	0.48	0.14	0.47	–	1.71
	3%	0.43	0.35	0.14	0.40	–	1.62

Number of Inclusions	Noise Level^a	TC^b
Number of Inclusions	Noise Level^a	Uncorrected	Corrected
1	0%	1^c	0.999
	1%	0.995	0.877
	2%	0.995	0.521
	3%	0.995	0.484
	5%	0.993	0.360
	8%	0.992	−0.165

2	0%	1^b	1^b
	1%	0.987	0.779
	2%	0.985	0.516
	3%	0.980	0.420

Number of Inclusions	Noise Level^a	SC^b		RM^c		RW^c
Number of Inclusions	Noise Level^a	Uncorrected	Corrected	Uncorrected	Corrected	Uncorrected	Corrected
1	0%	0.87	0.93	0.65	0.96	1.23	1.05
	1%	0.87	0.90	0.65	0.96	1.23	1.05
	2%	0.87	0.80	0.65	0.93	1.12	1.12
	3%	0.87	0.70	0.65	0.87	1.12	1.07
	5%	0.87	0.56	0.65	0.85	1.15	0.98
	8%	0.86	0.38	0.65	0.83	1.12	1.07
2	0%	0.43	0.65	0.14	0.49	–	1.46
	1%	0.43	0.62	0.14	0.48	–	1.46
	2%	0.43	0.48	0.14	0.47	–	1.71
	3%	0.43	0.35	0.14	0.40	–	1.62

Number of Inclusions	Noise Level^a	TC^b
Number of Inclusions	Noise Level^a	Uncorrected	Corrected
1	0%	1^c	0.999
	1%	0.995	0.877
	2%	0.995	0.521
	3%	0.995	0.484
	5%	0.993	0.360
	8%	0.992	−0.165

2	0%	1^b	1^b
	1%	0.987	0.779
	2%	0.985	0.516
	3%	0.980	0.420

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Applied Optics