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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 2, Iss. 5 — May. 17, 2007

High-resolution frequency-domain second-harmonic optical coherence tomography

Jianping Su, Ivan V. Tomov, Yi Jiang, and Zhongping Chen  »View Author Affiliations


Applied Optics, Vol. 46, Issue 10, pp. 1770-1775 (2007)
http://dx.doi.org/10.1364/AO.46.001770


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Abstract

We used continuum generated in an 8.5  cm long fiber by a femtosecond Yb fiber laser to improve threefold the axial resolution of frequency domain second-harmonic optical coherence tomography (SH-OCT) to 12 μ m . The acquisition time was shortened by more than 2 orders of magnitude compared to the time-domain SH-OCT. The system was applied to image biological tissue of fish scales, pig leg tendon, and rabbit eye sclera. Highly organized collagen fibrils can be visualized in the recorded images. Polarization dependence on the SH has been used to obtain polarization resolved images.

© 2007 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(190.4160) Nonlinear optics : Multiharmonic generation

ToC Category:
Optical Coherence Tomography

History
Original Manuscript: June 23, 2006
Manuscript Accepted: September 15, 2006
Published: March 13, 2007

Virtual Issues
Vol. 2, Iss. 5 Virtual Journal for Biomedical Optics

Citation
Jianping Su, Ivan V. Tomov, Yi Jiang, and Zhongping Chen, "High-resolution frequency-domain second-harmonic optical coherence tomography," Appl. Opt. 46, 1770-1775 (2007)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-46-10-1770

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