Characterization of a commercialized SERS-active substrate and its application to the identification of intact Bacillus endospores
Applied Optics, Vol. 46, Issue 18, pp. 3878-3890 (2007)
http://dx.doi.org/10.1364/AO.46.003878
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Abstract
Surface-enhanced-Raman-spectroscopy (SERS) can be made an attractive approach for the
identification of Raman-active compounds and biological materials (i.e., toxins, viruses, or intact
bacterial cells or spores) through development of reproducible, spatially uniform SERS-active
substrates. Recently, reproducible (from substrate to substrate), spatially homogeneous (over large
areas) SERS-active substrates have been commercialized and are now available in the marketplace. Scanning electron microscopy and high-resolution, tapping-mode atomic force microscopy
have been used to analyze these novel plasmonic surfaces for topographical consistency.
Additionally, we have assessed, by wavelength-tunable microreflectance spectrometry, the spatial
distribution of the localized surface plasmon resonance (LSPR) across a single substrate surface as
well as the LSPR
© 2007 Optical Society of America
OCIS Codes
(170.1580) Medical optics and biotechnology : Chemometrics
(300.6450) Spectroscopy : Spectroscopy, Raman
ToC Category:
Spectroscopy
History
Original Manuscript: December 22, 2006
Revised Manuscript: March 5, 2007
Manuscript Accepted: March 7, 2007
Published: May 31, 2007
Virtual Issues
Vol. 2, Iss. 7 Virtual Journal for Biomedical Optics
Citation
Troy A. Alexander and Dianna M. Le, "Characterization of a commercialized SERS-active substrate and its application to the identification of intact Bacillus endospores," Appl. Opt. 46, 3878-3890 (2007)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-46-18-3878
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