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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 2, Iss. 9 — Sep. 26, 2007

Determination of optical probe interrogation field of near-infrared reflectance: phantom and Monte Carlo study

Ali N. Bahadur, Cole A. Giller, Dheerendra Kashyap, and Hanli Liu  »View Author Affiliations


Applied Optics, Vol. 46, Issue 23, pp. 5552-5561 (2007)
http://dx.doi.org/10.1364/AO.46.005552


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Abstract

An optical probe used to localize human brain tissues in vivo has been reported previously. It was able to sense the underlying tissue structure with an optical interrogation field, termed as “look ahead distance” (LAD). A new side-firing probe has been designed with its optical window along its side. We have defined the optical interrogation field of the new side probe as “look aside distance” (LASD). The purpose of this study is to understand the dependence of the LAD and LASD on the optical properties of tissue, the light source intensity, and the integration time of the detector, using experimental and computational methods. The results show that a decrease in light intensity does decrease the LAD and LASD and that an increase in integration time of detection may not necessarily improve the depths of LAD and LASD. Furthermore, Monte Carlo simulation results suggest that the LAD∕LASD decreases with an increase in reduced scattering coefficient to a point, after which the LAD∕LASD remains constant. We expect that an optical interrogation field of a tip or side probe is approximately 1–2 mm in white matter and 2–3.5 mm in gray matter. These conclusions will help us optimally manipulate the parameter settings during surgery and determine the spatial resolution of the probe.

© 2007 Optical Society of America

OCIS Codes
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics
(290.1990) Scattering : Diffusion
(290.7050) Scattering : Turbid media

ToC Category:
Scattering

History
Original Manuscript: July 14, 2006
Revised Manuscript: January 25, 2007
Manuscript Accepted: March 23, 2007
Published: August 7, 2007

Virtual Issues
Vol. 2, Iss. 9 Virtual Journal for Biomedical Optics

Citation
Ali N. Bahadur, Cole A. Giller, Dheerendra Kashyap, and Hanli Liu, "Determination of optical probe interrogation field of near-infrared reflectance: phantom and Monte Carlo study," Appl. Opt. 46, 5552-5561 (2007)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-46-23-5552


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References

  1. R. F. Bonner, R. Nossal, S. Havlin, and G. H. Weiss, "Model for photon migration in turbid biological media," J. Opt. Soc. Am. A 4, 423-432 (1987). [CrossRef] [PubMed]
  2. T. J. Farrell and M. S. Patterson, "A diffusion theory model of spatially resolved, steady state diffuse reflectance for the non-invasive determination of tissue optical properties in vivo," Med. Phys. 19, 880-888 (1992). [CrossRef]
  3. R. Richards-Kortum, "Quantitative optical spectroscopy for tissue diagnosis," Annu. Rev. Phys. Chem. 47, 555-606 (1996). [CrossRef] [PubMed]
  4. H. Dehghani, D. T. Delphy, and S. R. Arridge, "Photon migration in non-scattering tissue and the effects on image reconstruction," Phys. Med. Biol. 44, 2897-2906 (1996). [CrossRef]
  5. G. H. Weiss, "Statistical properties of the penetration of photons into a semi-infinite turbid medium: a random-walk analsyis," Appl. Opt. 37, 3558-3563 (1998). [CrossRef]
  6. M. Johns, C. A. Giller, and H. Liu, "Computational and in-vivo investigation of optical reflectance from human brain to assist neurosurgery," J. Biomed. Opt. 3, 437-445 (1998). [CrossRef]
  7. C. A. Giller, M. Johns, and H. Liu, "Use of an intracranial near-infrared probe for localization during stereotactic surgery for movement disorders," J. Neurosurg. 93, 498-505 (2000). [CrossRef] [PubMed]
  8. C. A. Giller, H. Liu, P. Gurnani, S. Victor, U. Yazdani, and D. C. German, "Validation of a near-infrared probe for detection of thin intracranial white matter structures," J. Neurosurg. 98, 1299-1306 (2003). [CrossRef] [PubMed]
  9. M. Krause, W. Fogel, and A. Heck, "Deep brain stimulation for the treatment of Parkinson's disease: subthalamic nucleus versus globus pallidus internus," J. Neurol. Neurosurg. Psychiatry 70, 464-470 (2001). [CrossRef] [PubMed]
  10. A. M. Lozano and F. Carella, "Physiologic studies in the human brain in movement disorders," Parkinsonism and related disorders 8, 455-458 (2002). [CrossRef] [PubMed]
  11. B. Piallat, A. Benazzouz, and A. L. Benabid, "Neuroprotective effect of choronic inactivation of the subthalamic nucleus in a rat model of Parkinson's disease," J. Neural Transm. , Suppl. 55, 2-13 (1992).
  12. M. Krause, W. Fogel, P. Mayer, M. Kloss, and V. Tronnier, "Chronic inhibition of the subthalamic nucleus in Parkinsons disease," J. Neurol. Sci. 219, 119-124 (2004). [CrossRef] [PubMed]
  13. K. J. Burchiel, V. C. Anderson, J. Favre, and J. P. Hammerstad, "Comparison of pallidal and subthalamic nucleus deep brain stimulation for advanced Parkinson's disease: results of a randomized, blinded pilot study," Neurosurgery 45, 1375-1384 (1999). [CrossRef] [PubMed]
  14. Z. Qian, S. Victor, Y. Gu, C. A. Giller, and H. Liu, "Look-ahead distance of a fiber probe used to assist neurosurgery: phantom and Monte Carlo study," Opt. Express 11, 92-103 (2003). [CrossRef]
  15. A. Alkhani and A. M. Lozano, "Pallidotomy for Parkinson's disease: a review of contemporary literature," J. Neurosurg. 94, 43-49 (2001). [CrossRef] [PubMed]
  16. R. S. Palur, C. Berk, M. Schulzer, and C. R. Honey, "A metaanalysis comparing the results of pallidotomy performed using microelectrode recording or macroelectrode stimulation," J. Neurosurg. 96, 1058-1062 (2002). [CrossRef] [PubMed]
  17. I. Driver, J. W. Feather, P. R. King, and J. B. Dawson, "The optical properties of aqueous suspensions of intralipid, a fat emulsion," Phy. Med. Biol. 34, 1927-1930 (1989). [CrossRef]
  18. J. Fishkin and E. Gratton, "Propagation of photon density waves in a strongly scattering media containing an absorbing semi-infinite plane bounded by a straight edge," J. Opt. Soc. Am. A 10, 127-140 (1993). [CrossRef] [PubMed]
  19. S. Fantini, M. A. Franceschini, J. Maier, S. Walker, B. Barbieri, and E. Gratton, "Frequency-domain multichannel optical detector for noninvasive tissue spectroscopy and oximetry," Opt. Eng. 34, 32-42 (1995). [CrossRef]
  20. M. Franceschini, S. Fantini, A. Cerrusi, B. Barbieri, B. Chance, and E. Gratton, "Quantitative spectroscopic determination of hemoglobin concentration and saturation in a turbid medium: analysis of the effect of water absorption," J. Biomed. Opt. 2, 147-153 (1997). [CrossRef]
  21. L. H. Wang, S. L. Jacques, and L. Q. Zheng, "MCML-Monte Carlo modeling of photon transport in multi-layered tissues," Comput. Methods Programs Biomed. 47, 131-146 (1995). [CrossRef] [PubMed]
  22. L. H. Wang, S. L. Jacques, and L. Q. Zheng, "CONV-Convolution for responses to a finite diameter photon beam incident on multi-layered tissues," Comput. Methods Programs Biomed. 54, 142-150 (1997). [CrossRef]
  23. URL:http://oilab.tamu.edu/mc.html.
  24. S. T. Flock, S. L. Jacques, B. C. Wilson, W. M. Star, and M. J. C. van Gemert, "Optical properties of intralipid: a phantom medium for light propagation studies," Lasers Surg. Med. 12, 510-519 (1992). [CrossRef] [PubMed]
  25. I. S. Saidi, S. L. Jacques, and F. K. Tittel, "Mie and Rayleigh modeling of visible-light scattering in neonatal skin," Appl. Opt. 34, 7410-7418 (1995). [CrossRef] [PubMed]
  26. U. Utzinger and R. Richards-Kortum, "Fundamentals of spectroscopy: fiber optic probes," in Encyclopedia of Spectroscopy and Spectrometry, John Lindon, George Tranter, and John Holmes, eds. (Academic, 1999).
  27. C. F. Van Swol, E. te Slaa, R. M. Verdaasdonk, J. J. de la Rosette, and T. A. Boon, "Variation output power of laser prostatectomy fibers: a need for power measurements," Urology 47, 672-677 (1996). [CrossRef] [PubMed]
  28. M. Johns, C. A. Giller, D. C. German, and H. Liu, "Determination of reduced scattering coefficient of biological tissue from a needle-like probe," Opt. Express 13, 4828-4842 (2005). [CrossRef] [PubMed]
  29. P. van der Zee, M. Essenpreis, and D. T. Delpy, "Optical properties of brain tissue," Proc. SPIE 1888, 454-465 (1993). [CrossRef]

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