OSA's Digital Library

Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 2, Iss. 10 — Oct. 31, 2007

Angular distribution of diffuse reflectance in biological tissue

Jinjun Xia and Gang Yao  »View Author Affiliations


Applied Optics, Vol. 46, Issue 26, pp. 6552-6560 (2007)
http://dx.doi.org/10.1364/AO.46.006552


View Full Text Article

Enhanced HTML    Acrobat PDF (1713 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

We measured angular-resolved diffuse reflectance in tissue samples of different anisotropic characteristics. Experimental measurements were compared with theoretical results based on the diffusion approximation. The results indicated that the angular distribution in isotropic tissue was the same as in isotropic phantoms. Under normal incidence, the measured angular profiles of diffuse reflectance approached the Lambertian distribution when the evaluation location was far away from the incident point. The skewed angular profiles observed under oblique incidence could be explained using the diffuse model. The anisotropic tissue structures in muscle showed clear effects on the measurements especially at locations close to the light incidence. However, when measuring across the muscle fiber orientations, the results were in good agreement with those obtained in isotropic samples.

© 2007 Optical Society of America

OCIS Codes
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.6930) Medical optics and biotechnology : Tissue
(170.7050) Medical optics and biotechnology : Turbid media
(290.1350) Scattering : Backscattering
(290.1990) Scattering : Diffusion

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: April 16, 2007
Revised Manuscript: June 4, 2007
Manuscript Accepted: June 21, 2007
Published: September 5, 2007

Virtual Issues
Vol. 2, Iss. 10 Virtual Journal for Biomedical Optics

Citation
Jinjun Xia and Gang Yao, "Angular distribution of diffuse reflectance in biological tissue," Appl. Opt. 46, 6552-6560 (2007)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-46-26-6552


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. R. R. Alfano and J. G. Fujimoto, eds., Advances in Optical Imaging and Photon Imaging, Vol. 2 of OSA Trends in Optics and Photonics Series (Optical Society of America, 1996).
  2. B. Chance and R. R. Alfano, eds., Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II, Proc. SPIE 2979 (1997).
  3. K. Sokolov, M. Follen, and R. Richards-Kortum, "Optical spectroscopy for detection of neoplasia," Curr. Opin. Chem. Biol. 6, 651-658 (2002). [CrossRef] [PubMed]
  4. I. J. Bigio and S. G. Bown, "Spectroscopic sensing of cancer and cancer therapy: current status of translational research," Cancer Biother. 3, 259-267 (2004).
  5. J. Sun, K. Fu, A. Wang, A. W. H. Lin, U. Utzinger, and R. Drezek, "Influence of fiber optic probe geometry on the applicability of inverse models of tissue reflectance spectroscopy: computational models and experimental measurements," Appl. Opt. 45, 8152-8162 (2005). [CrossRef]
  6. J. Y. Qu, Z. Huang, and J. Hua, "Excitation-and-collection geometry insensitive fluorescence imaging of tissue-simulating turbid media," Appl. Opt. 39, 3344-3356 (2000). [CrossRef]
  7. S. C. Gebhart, A. Mahadevan-Jansen, and W. C. Lin, "Experimental and simulated angular profiles of fluorescence and diffuse reflectance emission from turbid media," Appl. Opt. 44, 4884-4901 (2005). [CrossRef] [PubMed]
  8. M. A. ElHelw, B. P. Lo, A. J. Chung, A. Darzi, and G. Z. Yang, "Photorealistic rendering of large tissue deformation for surgical simulation," Lecture Notes Comput. Sci. 3217, 355-362 (2004). [CrossRef]
  9. A. Kienle, L. Lilge, M. S. Patterson, R. Hibst, R. Steiner, and B. C. Wilson, "Spatially resolved absolute diffuse reflectance measurements for noninvasive determination of the optical scattering and absorption coefficients of biological tissue," Appl. Opt. 35, 2304-2314 (1996). [CrossRef] [PubMed]
  10. K. M. Hebeda, T. Menovsky, J. F. Beek, J. G. Wolbers, and M. J. C. van Gemert, "Light propagation in the brain depends on nerve fiber orientation," Neurosurgery 35, 720-724 (1994). [CrossRef] [PubMed]
  11. F. Bevilacqua, P. Marquet, O. Coquoz, and C. Depeursinge, "Role of tissue structure in photon migration through breast tissues," Appl. Opt. 36, 44-51 (1997). [CrossRef] [PubMed]
  12. S. Nickell, M. Hermann, M. Essenpreis, T. J. Farrell, U. Kramer, and M. S. Patterson, "Anisotropy of light propagation in human skin," Phys. Med. Biol. 45, 2873-2886 (2000). [CrossRef] [PubMed]
  13. J. Ranasinghesagara, F. Hsieh, and G. Yao, "A photon migration method for quantifying fiber formation in meat analogs," J. Food Sci. 71, E227-231 (2006). [CrossRef]
  14. A. Kienle and R. Hibst, "Light guiding in biological tissue due to scattering," Phys. Rev. Lett. 97, 018104 (2006). [CrossRef] [PubMed]
  15. J. Ranasinghesagara and G. Yao, "Imaging 2D diffuse reflectance in skeleton muscle," Opt. Express 15, 3998-4007 (2007). [CrossRef] [PubMed]
  16. A. Ishimaru, Wave Propagation and Scattering in Random Media (Academic, 1978), Chaps. 7 and 9.
  17. A. J. Welch and M. J. C. Van, Optical-Thermal Response of Laser-Irradiated Tissue (Plenum Press, 1995).
  18. S. T. Flock, B. C. Wilson, and M. S. Patterson, "Monte-Carlo modeling of light propagation in highly scattering tissues-II: comparison with measurements in phantoms," IEEE Trans. Biomed. Eng. 36, 1169-1173 (1989). [CrossRef] [PubMed]
  19. G. Mitic, J. Kolzer, J. Otto, E. Plies, G. Solkner, and W. Zinth, "Time-gated transillumination of biological tissues and tissue-like phantoms," Appl. Opt. 33, 6699-6710 (1994). [CrossRef] [PubMed]
  20. M. S. Patterson, B. Chance, and B. C. Wilson, "Time resolved reflectance and transmittance for the noninvasive measurement of tissue optical properties," Appl. Opt. 28, 2331-2336 (1989). [CrossRef] [PubMed]
  21. T. J. Farrell, M. S. Patterson, and B. Wilson, "A diffusion theory model of spatially resolved, steady-state diffuse reflectance for the noninvasive determination of tissue optical properties in vivo," Med. Phys. 19, 879-888 (1992). [CrossRef] [PubMed]
  22. L.-H. Wang and S. L. Jacques, "Use of a laser beam with an oblique angle of incidence to measure the reduced scattering coefficient of a turbid medium," Appl. Opt. 34, 2362-2366 (1995). [CrossRef] [PubMed]
  23. S.-P. Lin, L.-H. Wang, S. L. Jacques, and F. K. Tittel, "Measurement of tissue optical properties by the use of oblique-incidence optical fiber reflectometry," Appl. Opt. 36, 136-143 (1997). [CrossRef] [PubMed]
  24. G. Marquez and L. Wang, "White light oblique incidence reflectometer for measuring absorption and reduced scattering spectra of tissue-like turbid media," Opt. Express 1, 454-460 (1997). [CrossRef] [PubMed]
  25. H. B. Jiang, G. Marquez, and L. H. Wang, "Particle sizing in concentrated suspensions by use of steady-state, continuous-wave photon-migration techniques," Opt. Lett. 23, 394-396 (1998). [CrossRef]
  26. A. Garcia-Uribe, N. Kehtarnavaz, G. Marquez, V. Prieto, M. Duvic, and L. H. Wang, "Skin cancer detection by spectroscopic oblique-incidence reflectometry: classification and physiological origins," Appl. Opt. 43, 2643-2650 (2004). [CrossRef] [PubMed]
  27. J. Xia, A. Weaver, D. E. Gerrard, and G. Yao, "Monitoring sarcomere structure changes in whole muscle using diffuse light reflectance," J. Biomed. Opt. 11, 040504 (2006). [CrossRef] [PubMed]
  28. T. Binzoni, C. Courvoisier, R. Giust, G. Tribillion, T. Gharbi, J. C. Hebden, T. S. Leung, J. Roux, and D. T. Delpy, "Anisotropic photon migration in human skeletal muscle," Phys. Med. Biol. 51, N79-N90 (2006). [CrossRef] [PubMed]
  29. G. Marquez, L. V. Wang, S. P. Lin, J. A. Schwartz, and S. L. Thomsen, "Anisotropy in the absorption and scattering spectra of chicken breast tissue," Appl. Opt. 28, 2318-2324 (1998).
  30. A. M. Pearson and R. B. Young, Muscle and Meat Biochemistry (Academic, 1989).

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited