Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Fiber-based multispeckle detection for time-resolved diffusing-wave spectroscopy: characterization and application to blood flow detection in deep tissue

Not Accessible

Your library or personal account may give you access

Abstract

We present a technique for the measurement of temporal field autocorrelation functions of multiply scattered light with subsecond acquisition time. The setup is based on the parallel detection and autocorrelation of intensity fluctuations from statistically equivalent but independent speckles using a fiber bundle, an array of avalanche photodiodes, and a multichannel autocorrelator with variable integration times between 6.5 and 104 ms. Averaging the autocorrelation functions from the different speckles reduces the integration time in diffusing-wave spectroscopy experiments drastically, thus allowing us to resolve nonstationary scatterer dynamics with single-trial measurements. We present applications of the technique to the measurement of arterial and venous blood flow in deep tissue. We find strong deviations both of the shape and characteristic decay time of autocorrelation functions recorded at different phases of the pulsation cycle from time-averaged autocorrelation functions.

© 2007 Optical Society of America

Full Article  |  PDF Article
More Like This
Pulsation-resolved deep tissue dynamics measured with diffusing-wave spectroscopy

Jun Li, Franck Jaillon, Gregor Dietsche, Georg Maret, and Thomas Gisler
Opt. Express 14(17) 7841-7851 (2006)

Activity of the human visual cortex measured non-invasively by diffusing-wave spectroscopy

Franck Jaillon, Jun Li, Gregor Dietsche, Thomas Elbert, and Thomas Gisler
Opt. Express 15(11) 6643-6650 (2007)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (7)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Equations (5)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved