Non-tissue-like features in the time-of-flight distributions of plastic tissue phantoms
Applied Optics, Vol. 47, Issue 13, pp. 2477-2485 (2008)
http://dx.doi.org/10.1364/AO.47.002477
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Abstract
We measure high-temporal-resolution time-of-flight distributions of picosecond laser pulses in the visible and near-infrared, scattered in the forward direction by solid and liquid phantoms, and compare them to those obtained by using ex vivo tissues. We demonstrate that time-of-flight distributions from solid phantoms made of Delrin, Nylon, and Teflon are modulated by ripples that are absent in the biological samples and disappear when the temporal and/or angular resolution of the measuring apparatus is decreased. This behavior prevents the use of such materials as tissue phantoms when spatial mode and time selection are required, such as in imaging methods exploiting early arriving photons.
© 2008 Optical Society of America
OCIS Codes
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.5280) Medical optics and biotechnology : Photon migration
(170.6920) Medical optics and biotechnology : Time-resolved imaging
(170.6930) Medical optics and biotechnology : Tissue
ToC Category:
Medical Optics and Biotechnology
History
Original Manuscript: July 25, 2007
Revised Manuscript: February 8, 2008
Manuscript Accepted: March 27, 2008
Published: April 29, 2008
Virtual Issues
Vol. 3, Iss. 6 Virtual Journal for Biomedical Optics
Citation
Luca Nardo, Adriano Brega, Maria Bondani, and Alessandra Andreoni, "Non-tissue-like features in the time-of-flight distributions of plastic tissue phantoms," Appl. Opt. 47, 2477-2485 (2008)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-47-13-2477
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