The low-temperature cavitational disruption by trains of laser pulses was demonstrated in water. The trains used in the experiment were generated by a Raman laser at a wavelength of $1626\mathrm{nm}$ . The mean value of the fragmentation threshold energy density per pulse in a train was estimated to be equal to ${7.2\times 10}^6\mathrm{J}/{\mathrm{m}}^3$ . The corresponding amplitude of the negative pressure had the order of $6–7\mathrm{bars}$ at a temperature jump of only about $2°\mathrm{C}$ . This result opens up prospects for developing precision nonthermal cavitational laser surgery.