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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 3, Iss. 12 — Dec. 1, 2008

Localization of adipose tissue embedded biliary tree vessels by use of near-infrared diffuse photon propagation models: a computational feasibility study

George Alexandrakis, Dharmendra Nadkar, Nimit L. Patel, Hanli Liu, and Edward H. Livingston  »View Author Affiliations


Applied Optics, Vol. 47, Issue 29, pp. 5261-5271 (2008)
http://dx.doi.org/10.1364/AO.47.005261


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Abstract

Biliary tree structures are embedded in adipose tissue and, therefore, cannot be visualized directly by the surgeon during cholecystectomy operations. This can lead to inadvertent injuries with serious complications for the patient. Computational studies were performed to assess the feasibility of noninvasively localizing these structures from spectrally resolved near-infrared reflectance measurements. Methodologies were developed for vessel localization, both on the adipose tissue surface and depthwise, by use of semi-infinite and two-layer models of diffuse photon propagation in tissues, respectively. The simulation results, along with some preliminary experimental measurements on tissue-simulating phantoms, prove the feasibility of these methods and show promise for their future clinical application.

© 2008 Optical Society of America

OCIS Codes
(170.1610) Medical optics and biotechnology : Clinical applications
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(290.1990) Scattering : Diffusion
(290.7050) Scattering : Turbid media

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: January 31, 2008
Revised Manuscript: July 15, 2008
Manuscript Accepted: August 22, 2008
Published: October 3, 2008

Virtual Issues
Vol. 3, Iss. 12 Virtual Journal for Biomedical Optics

Citation
George Alexandrakis, Dharmendra Nadkar, Nimit L. Patel, Hanli Liu, and Edward H. Livingston, "Localization of adipose tissue embedded biliary tree vessels by use of near-infrared diffuse photon propagation models: a computational feasibility study," Appl. Opt. 47, 5261-5271 (2008)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-47-29-5261

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