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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 4, Iss. 6 — May. 26, 2009

Complete optical neurophysiology: toward optical stimulation and recording of neural tissue

Fred A. Wininger, Jennifer L. Schei, and David M. Rector  »View Author Affiliations


Applied Optics, Vol. 48, Issue 10, pp. D218-D224 (2009)
http://dx.doi.org/10.1364/AO.48.00D218


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Abstract

Direct optical methods to stimulate and record neural activity provide artifact-free, noninvasive, and noncontact neurophysiological procedures. For stimulation, focused mid-infrared light alters membrane potential and activates individual neural processes. Simultaneous intrinsic scattered light parameters, including birefringence changes, can record neural activity with signals similar to potentiometric dyes. The simultaneous combination of optical stimulation and optical recording techniques provide the potential for powerful tools that may someday remove the need for invasive wires during electrophysiological recordings.

© 2009 Optical Society of America

OCIS Codes
(140.3070) Lasers and laser optics : Infrared and far-infrared lasers
(170.3890) Medical optics and biotechnology : Medical optics instrumentation

History
Original Manuscript: July 22, 2008
Revised Manuscript: October 7, 2008
Manuscript Accepted: January 30, 2009
Published: March 2, 2009

Virtual Issues
Vol. 4, Iss. 6 Virtual Journal for Biomedical Optics

Citation
Fred A. Wininger, Jennifer L. Schei, and David M. Rector, "Complete optical neurophysiology: toward optical stimulation and recording of neural tissue," Appl. Opt. 48, D218-D224 (2009)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-48-10-D218


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