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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 4, Iss. 8 — Jul. 30, 2009

Frequency domain measurements on turbid media with strong absorption using the P N approximation

Christof Baltes and Gregory W. Faris  »View Author Affiliations


Applied Optics, Vol. 48, Issue 16, pp. 2991-3000 (2009)
http://dx.doi.org/10.1364/AO.48.002991


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Abstract

We have applied the frequency-domain technique to measurement of the optical properties of turbid media with strong absorption in the infinite medium limit. Absorption coefficients up to 2.3 cm 1 for a modified scattering coefficient of 4.3 cm 1 are studied, which corresponds to a reduced scattering albedo of 0.65. Low phase noise and good phase stability are required for these low albedo conditions. As the degree of absorption increases, the phase changes are reduced while amplitude changes increase. For this reason, correction of amplitude-phase cross talk is essential to achieve accurate measurements with strong absorption. Careful control of stray reflections is required to properly measure amplitude-phase cross talk. Because the diffusion approximation becomes less accurate, measurements are compared to calculations performed in the P N approximation, which is essentially an exact solution for the infinite medium limit. Agreement between theory and experiment is only obtained when correction for amplitude-phase cross talk is performed. These measurements can provide a good method for testing amplitude-phase cross talk.

© 2009 Optical Society of America

OCIS Codes
(170.5270) Medical optics and biotechnology : Photon density waves
(170.5280) Medical optics and biotechnology : Photon migration
(290.1990) Scattering : Diffusion
(290.4210) Scattering : Multiple scattering
(290.7050) Scattering : Turbid media

ToC Category:
Scattering

History
Original Manuscript: September 12, 2008
Revised Manuscript: March 30, 2009
Manuscript Accepted: April 21, 2009
Published: May 21, 2009

Virtual Issues
Vol. 4, Iss. 8 Virtual Journal for Biomedical Optics

Citation
Christof Baltes and Gregory W. Faris, "Frequency domain measurements on turbid media with strong absorption using the PN approximation," Appl. Opt. 48, 2991-3000 (2009)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-48-16-2991

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