Off-axis integrated cavity output spectroscopy with a mid-infrared interband cascade laser for real-time breath ethane measurements
Applied Optics, Vol. 48, Issue 4, pp. B73-B79 (2009)
http://dx.doi.org/10.1364/AO.48.000B73
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Abstract
Cavity-enhanced tunable diode laser absorption spectroscopy is an attractive method for measuring small concentrations of gaseous species. Ethane is a breath biomarker of lipid peroxidation initiated by reactive oxygen species. A noninvasive means of quickly quantifying oxidative stress status has the potential for broad clinical application. We present a simple, compact system using off-axis integrated cavity output spectroscopy with an interband cascade laser and demonstrate its use in real-time measurements of breath ethane. We demonstrate a detection sensitivity of
© 2008 Optical Society of America
OCIS Codes
(280.0280) Remote sensing and sensors : Remote sensing and sensors
(300.0300) Spectroscopy : Spectroscopy
History
Original Manuscript: July 17, 2008
Revised Manuscript: October 24, 2008
Manuscript Accepted: November 1, 2008
Published: December 8, 2008
Virtual Issues
Vol. 4, Iss. 4 Virtual Journal for Biomedical Optics
Citation
Krishnan R. Parameswaran, David I. Rosen, Mark G. Allen, Alan M. Ganz, and Terence H. Risby, "Off-axis integrated cavity output spectroscopy with a mid-infrared interband cascade laser for real-time breath ethane measurements," Appl. Opt. 48, B73-B79 (2009)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-48-4-B73
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