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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 5, Iss. 10 — Jul. 19, 2010

Photoacoustic waves generated in blood studied using pulsed digital holography

Erik Olsson, Per Gren, and Mikael Sjödahl  »View Author Affiliations


Applied Optics, Vol. 49, Issue 16, pp. 3053-3058 (2010)
http://dx.doi.org/10.1364/AO.49.003053


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Abstract

We studied photoacoustic waves using pulsed digital holography. The acoustic waves were generated in a reindeer blood target by absorption of an IR laser pulse, λ = 1064 nm and pulse length = 12 ns . The acoustic pressure waves were then imaged in water using a second collimated laser pulse at λ = 532 nm 2 μs after the first IR pulse. Quantitative information on acoustic wave properties such as three-dimensional shape and pressure distribution was calculated by applying the inverse Radon transform on the recorded projection. The pressure pulse had a flat and sharp front parallel with the blood surface, which indicates that the pressure was generated at the blood surface. The generated pressure was proportional to the laser fluence with the proportionality constant equal to 1.8 ± 0.3 cm 1 . According to existing data, the proportionality constant should be 1.4 cm 1 for oxygenated human blood, which made our calculations probable.

© 2010 Optical Society of America

OCIS Codes
(090.2880) Holography : Holographic interferometry
(110.5125) Imaging systems : Photoacoustics

ToC Category:
Holography

History
Original Manuscript: November 11, 2009
Revised Manuscript: March 31, 2010
Manuscript Accepted: April 30, 2010
Published: May 25, 2010

Virtual Issues
Vol. 5, Iss. 10 Virtual Journal for Biomedical Optics

Citation
Erik Olsson, Per Gren, and Mikael Sjödahl, "Photoacoustic waves generated in blood studied using pulsed digital holography," Appl. Opt. 49, 3053-3058 (2010)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-49-16-3053

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