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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 5, Iss. 12 — Sep. 30, 2010

Single-step replication of a highly integrated PDMS optofluidic analysis system

Martin Amberg, Sebastian Stoebenau, and Stefan Sinzinger  »View Author Affiliations


Applied Optics, Vol. 49, Issue 22, pp. 4326-4330 (2010)
http://dx.doi.org/10.1364/AO.49.004326


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Abstract

Micromilling is a promising technology for the fabrication of surface profiles with optical quality. We present a highly integrated optofluidic system made of polydimethylsiloxane (PDMS). The system is replicated in a single-step process from a micromilled polymethyl methacrylate master mold. It already includes the reservoirs, the channel system, as well as the optical interconnect surfaces for high numerical aperture objectives. We demonstrate the potential of this approach by laser-based three-dimensional optical manipulation within the replicated system. To our knowledge, this is the first time that a PDMS membrane is used as a well-defined channel wall for an optical trapping setup.

© 2010 Optical Society of America

OCIS Codes
(130.0130) Integrated optics : Integrated optics
(180.0180) Microscopy : Microscopy
(350.4855) Other areas of optics : Optical tweezers or optical manipulation

ToC Category:
Optical Tweezers or Optical Manipulation

History
Original Manuscript: February 26, 2010
Revised Manuscript: June 28, 2010
Manuscript Accepted: July 2, 2010
Published: July 30, 2010

Virtual Issues
Vol. 5, Iss. 12 Virtual Journal for Biomedical Optics

Citation
Martin Amberg, Sebastian Stoebenau, and Stefan Sinzinger, "Single-step replication of a highly integrated PDMS optofluidic analysis system," Appl. Opt. 49, 4326-4330 (2010)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-49-22-4326

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