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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 6, Iss. 7 — Jul. 27, 2011

Spatial coherence effect on layer thickness determination in narrowband full-field optical coherence tomography

Avner Safrani and Ibrahim Abdulhalim  »View Author Affiliations


Applied Optics, Vol. 50, Issue 18, pp. 3021-3027 (2011)
http://dx.doi.org/10.1364/AO.50.003021


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Abstract

Longitudinal spatial coherence (LSC) is determined by the spatial frequency content of an optical beam. The use of lenses with a high numerical aperture (NA) in full-field optical coherence tomography and a narrowband light source makes the LSC length much shorter than the temporal coherence length, hence suggesting that high-resolution 3D images of biological and multilayered samples can be obtained based on the low LSC. A simplified model is derived, supported by experimental results, which describes the expected interference output signal of multilayered samples when high-NA lenses are used together with a narrowband light source. An expression for the correction factor for the layer thickness determination is found valid for high-NA objectives. Additionally, the method was applied to a strongly scattering layer, demonstrating the potential of this method for high-resolution imaging of scattering media.

© 2011 Optical Society of America

OCIS Codes
(110.0110) Imaging systems : Imaging systems
(110.1650) Imaging systems : Coherence imaging
(110.4500) Imaging systems : Optical coherence tomography
(120.0120) Instrumentation, measurement, and metrology : Instrumentation, measurement, and metrology
(120.3180) Instrumentation, measurement, and metrology : Interferometry
(180.0180) Microscopy : Microscopy

ToC Category:
Coherence and Statistical Optics

History
Original Manuscript: January 19, 2011
Revised Manuscript: March 27, 2011
Manuscript Accepted: April 30, 2011
Published: June 16, 2011

Virtual Issues
Vol. 6, Iss. 7 Virtual Journal for Biomedical Optics

Citation
Avner Safrani and Ibrahim Abdulhalim, "Spatial coherence effect on layer thickness determination in narrowband full-field optical coherence tomography," Appl. Opt. 50, 3021-3027 (2011)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-50-18-3021

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