OSA's Digital Library

Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 7, Iss. 2 — Feb. 1, 2012

Quantification of glistenings in intraocular lenses using a ballistic-photon removing integrating-sphere method

Do-Hyun Kim, Robert H. James, Robert J. Landry, Don Calogero, James Anderson, and Ilko K. Ilev  »View Author Affiliations


Applied Optics, Vol. 50, Issue 35, pp. 6461-6467 (2011)
http://dx.doi.org/10.1364/AO.50.006461


View Full Text Article

Enhanced HTML    Acrobat PDF (341 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

An alternative method for quantification of glistenings in intraocular lenses (IOLs) using an integrating sphere with an adjustable back aperture to remove ballistic photons is presented. Glistenings in soft IOLs have been known for more than a decade; however, their severity and visual impact are still under investigation. A number of studies have been made to quantitatively describe glistenings in IOLs. Quantization and precise grading of IOLs will provide needed information to evaluate the severity and visual impact of glistenings in patients. We investigated the use of a simple modification of an integrating-sphere method to eliminate ballistic photons to quantitatively measure scattered light from glistenings in IOLs. The method described in this paper provides a simple and effective way to quantitatively characterize glistenings in vitro. It may be especially useful to quantify scattering associated with low-grade glistenings where the density of the scattering centers is low. Finally, the modified integrating-sphere method may also be generally applicable to quantitatively characterize scattering from other optical media.

OCIS Codes
(120.5820) Instrumentation, measurement, and metrology : Scattering measurements
(170.4460) Medical optics and biotechnology : Ophthalmic optics and devices
(330.4595) Vision, color, and visual optics : Optical effects on vision

ToC Category:
Instrumentation, Measurement, and Metrology

History
Original Manuscript: June 17, 2011
Revised Manuscript: August 19, 2011
Manuscript Accepted: August 22, 2011
Published: December 2, 2011

Virtual Issues
Vol. 7, Iss. 2 Virtual Journal for Biomedical Optics

Citation
Do-Hyun Kim, Robert H. James, Robert J. Landry, Don Calogero, James Anderson, and Ilko K. Ilev, "Quantification of glistenings in intraocular lenses using a ballistic-photon removing integrating-sphere method," Appl. Opt. 50, 6461-6467 (2011)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-50-35-6461


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. N. Ballin, “Glistenings in injection-molded lens,” J. Am. Intra-Ocul. Implant Soc. 10, 473 (1984).
  2. K. M. Klos, R. Richter, O. E. Schnaudigel, and C. Ohrloff, “Image analysis of implanted rigid and foldable intraocular lenses in human eyes using Scheimpflug photography,” Ophthalmic Res. 31, 130–133 (1999). [CrossRef] [PubMed]
  3. L. Werner, “Glistenings and surface light scattering in intraocular lenses,” J. Cataract Refract. Surg. 36, 1398–1420(2010). [CrossRef] [PubMed]
  4. D. Tognetto, L. Toto, G. Sanguinetti, and G. Ravalico, “Glistenings in foldable intraocular lenses,” J. Cataract Refract. Surg. 28, 1211–1216 (2002). [CrossRef] [PubMed]
  5. M. Ayaki, H. Nishihara, S. Yaguchi, and R. Koide, “Surfactant induced glistenings: surface active ingredients in ophthalmic solutions may enhance water entry into the voids of implanted acrylic intraocular lenses,” J. Long-term Eff. Med. Implants 16, 451–457 (2006).
  6. S. Arshinoff, “Does a tight capsular bag cause glistenings?,” J. Cataract Refract. Surg. 24, 6 (1998). [PubMed]
  7. H. B. Dick, R. J. Olson, A. J. Augustin, O. Schwenn, G. Magdowski, and N. Pfeiffer, “Vacuoles in the AcrySof_ intraocular lens as factor of the presence of serum in aqueous humor,” Ophthal. Res. 33, 61–67 (2001). [CrossRef]
  8. N. Z. Gregori, T. S. Spencer, N. Mamalis, and R. J. Olson, “In vitro comparison of glistening formation among hydrophobic acrylic intraocular lenses,” J. Cataract Refract. Surg. 28, 1262–1268 (2002). [CrossRef] [PubMed]
  9. D. K. Dhaliwal, N. Mamalis, R. J. Olson, A. S. Crandall, P. Zimmerman, O. C. Alldredge, F. J. Durcan, and O. Omar, “Visual significance of glistenings seen in the AcrySof intraocular lens,” J. Cataract Refract. Surg. 22, 452–457 (1996). [PubMed]
  10. G. Christiansen, F. J. Durcan, R. J. Olson, and K. Christiansen, “Glistenings in the AcrySof intraocular lens: pilot study,” J. Cataract Refract. Surg. 27, 728–733 (2001). [CrossRef] [PubMed]
  11. T. Oshika, Y. Shiokawa, S. Amano, and K. Mitomo, “Influence of glistenings on the optical quality of acrylic foldable intraocular lens,” Br. J. Ophthalmol. 85, 1034–1037 (2001). [CrossRef] [PubMed]
  12. U. Gunenc, F. H. Oner, S. Tongal, and M. Ferliel, “Effects on visual function of glistenings and folding marks in AcrySof intraocular lenses,” J. Cataract Refract. Surg. 27, 1611–1614(2001). [CrossRef] [PubMed]
  13. A. Cisneros-Lanuza, M. Hurtado-Sarrio, A. Duch-Samper, R. Gallego-Pinazo, and J. L. Menezo-Rozale, “Glistenings in the Artiflex phakic intraocular lens,” J. Cataract Refract. Surg. 33, 1405–1408 (2007). [CrossRef] [PubMed]
  14. E. Wilkins and R. J. Olson, “Glistenings with long-term follow-up of the Surgidev B20/20 polymethylmethacrylate intraocular lens,” Am. J. Ophthalmol. 132, 783–785(2001). [CrossRef] [PubMed]
  15. A. Waite, N. Faulkner, and R. J. Olson, “Glistenings in the single-piece, hydrophobic, acrylic intraocular lenses,” Am. J. Ophthalmol. 144, 143–144 (2007). [CrossRef] [PubMed]
  16. A. Behndig and E. Mönestam, “Quantification of glistenings in intraocular lenses using Scheimpflug photography,” J. Cataract Refract. Surg. 35, 14–17 (2009). [CrossRef]
  17. R. J. Mackool and J. Colin, “Limitations of Scheimpflug photography in quantifying glistenings,” J. Cataract Refract. Surg. 35, 1480–1481 (2009). [CrossRef] [PubMed]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

Figures

Fig. 1 Fig. 2 Fig. 3
 
Fig. 4
 

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited