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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 8, Iss. 7 — Aug. 1, 2013

Design and validation of two optical beacons for guidewire localization in breast-conserving surgery

Rebecca Anne Wilson, Stephen A. McAleavey, Linda M. Schiffhauer, and James Zavislan  »View Author Affiliations


Applied Optics, Vol. 52, Issue 17, pp. 4024-4034 (2013)
http://dx.doi.org/10.1364/AO.52.004024


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Abstract

Stereotactically placed guidewires are used for indicating the location of a nonpalpable carcinoma in breast-conserving surgery. Pathologists use the end of the embedded guidewire to guide sectioning during intraoperative margin assessment, but they do not currently have a tool to indicate the location of the guidewire end for informed sectioning. We present analysis and experimental testing of two optical methods for localizing the end of an embedded fiber-optic guidewire: the first uses irradiance emitted from the fiber to indicate the location of the guidewire end, while the second system uses the fiber optic to create a photoacoustic pulse for localization. Both systems locate the end of the guidewire within ±5mm, which ensures that the lesion of interest is bisected during sectioning. The accuracy of the irradiance-based beacon is influenced by standard margin paints, so the photoacoustic beacon proved more useful under current tissue-handling protocols.

© 2013 Optical Society of America

OCIS Codes
(170.1610) Medical optics and biotechnology : Clinical applications
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(170.4730) Medical optics and biotechnology : Optical pathology
(290.1990) Scattering : Diffusion
(290.7050) Scattering : Turbid media
(110.5125) Imaging systems : Photoacoustics

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: January 3, 2013
Revised Manuscript: April 11, 2013
Manuscript Accepted: April 19, 2013
Published: June 7, 2013

Virtual Issues
Vol. 8, Iss. 7 Virtual Journal for Biomedical Optics

Citation
Rebecca Anne Wilson, Stephen A. McAleavey, Linda M. Schiffhauer, and James Zavislan, "Design and validation of two optical beacons for guidewire localization in breast-conserving surgery," Appl. Opt. 52, 4024-4034 (2013)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-52-17-4024

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