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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 8, Iss. 8 — Sep. 4, 2013

Pulsed ultrasound modulated optical tomography utilizing the harmonic response of lock-in detection

H. Ruan, M. L. Mather, and S. P. Morgan  »View Author Affiliations


Applied Optics, Vol. 52, Issue 19, pp. 4755-4762 (2013)
http://dx.doi.org/10.1364/AO.52.004755


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Abstract

Ultrasound modulated optical tomography (USMOT) can image the optical properties of a scattering medium at a spatial resolution approaching that of ultrasound (US). A lock-in parallel speckle detection technique is proposed to detect pulsed US modulated light using a multipixel detector. The frequency components of the pass band match those of the US pulse train and provide efficient detection. The modulation depth is extracted by taking the difference between a pair of speckle patterns modulated by a pair of phase-inversed US bursts. Modification to pulse inversion mode enables the second harmonic US modulation due to nonlinear US propagation to be detected.

© 2013 Optical Society of America

OCIS Codes
(110.6150) Imaging systems : Speckle imaging
(110.0113) Imaging systems : Imaging through turbid media

ToC Category:
Imaging Systems

History
Original Manuscript: May 31, 2013
Revised Manuscript: May 31, 2013
Manuscript Accepted: June 1, 2013
Published: June 28, 2013

Virtual Issues
Vol. 8, Iss. 8 Virtual Journal for Biomedical Optics

Citation
H. Ruan, M. L. Mather, and S. P. Morgan, "Pulsed ultrasound modulated optical tomography utilizing the harmonic response of lock-in detection," Appl. Opt. 52, 4755-4762 (2013)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-52-19-4755

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