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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 8, Iss. 8 — Sep. 4, 2013

Virtual source method for diffuse optical imaging

Hakan Erkol and Mehmet Burcin Unlu  »View Author Affiliations


Applied Optics, Vol. 52, Issue 20, pp. 4933-4940 (2013)
http://dx.doi.org/10.1364/AO.52.004933


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Abstract

The Green’s function for diffusive wave propagation can be obtained by utilizing the representation theorems of the convolution type and the correlation type. In this work, the Green’s function is retrieved by making use of the Robin boundary condition and the representation theorems for diffusive media. The diffusive Green’s function between two detectors for photon flux is calculated by combining detector readings due to point light sources and utilizing virtual light sources at the detector positions in optical tomography. Two dimensional simulations for a circular region with eight sources and eight detectors located on the boundary are performed using a finite element method to demonstrate the feasibility of virtual sources. The most important potential application would be the replacement of noisy measurements with synthetic measurements that are provided by the virtual sources. This becomes an important issue in small animal and human studies. In addition, the same method may also be used to reduce the imaging time.

© 2013 Optical Society of America

OCIS Codes
(000.3860) General : Mathematical methods in physics
(170.3660) Medical optics and biotechnology : Light propagation in tissues
(170.5270) Medical optics and biotechnology : Photon density waves

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: January 31, 2013
Revised Manuscript: April 16, 2013
Manuscript Accepted: May 20, 2013
Published: July 9, 2013

Virtual Issues
Vol. 8, Iss. 8 Virtual Journal for Biomedical Optics

Citation
Hakan Erkol and Mehmet Burcin Unlu, "Virtual source method for diffuse optical imaging," Appl. Opt. 52, 4933-4940 (2013)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ao-52-20-4933

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