We present a new compact system for time-domain diffuse optical spectroscopy of highly scattering media operating in the wavelength range from 1100 nm to 1700 nm. So far, this technique has been exploited mostly up to 1100 nm: we extended the spectral range by means of a pulsed supercontinuum light source at a high repetition rate, a prism to spectrally disperse the radiation, and a time-gated InGaAs/InP single-photon avalanche diode working up to 1700 nm. A time-correlated single-photon counting board was used as processing electronics. The system is characterized by linear behavior up to absorption values of about 3.4 cm−1 where the relative error is 17%. A first measurement performed on lipids is presented: the absorption spectrum shows three major peaks at 1200 nm, 1400 nm, and 1700 nm.
Vol. 7, Iss. 10 Virtual Journal for Biomedical Optics
Ilaria Bargigia, Alberto Tosi, Andrea Bahgat Shehata, Adriano Della Frera, Andrea Farina, Andrea Bassi, Paola Taroni, Alberto Dalla Mora, Franco Zappa, Rinaldo Cubeddu, and Antonio Pifferi, "Time-Resolved Diffuse Optical Spectroscopy up to 1700 nm by Means of a Time-Gated InGaAs/InP Single-Photon Avalanche Diode," Appl. Spectrosc. 66, 944-950 (2012)