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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 2, Iss. 11 — Nov. 26, 2007

Corneal minimal visible lesion thresholds for 2.0 μ m laser radiation

Bo Chen, Jeffrey Oliver, Soumak Dutta, Grady H. Rylander III, Sharon L. Thomsen, and Ashley J. Welch  »View Author Affiliations


JOSA A, Vol. 24, Issue 10, pp. 3080-3088 (2007)
http://dx.doi.org/10.1364/JOSAA.24.003080


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Abstract

To support refinement of the ANSI Maximum Permissible Exposure safety limits, a series of experiments were conducted in vivo on Dutch Belted rabbit corneas to determine corneal minimum visible lesion thresholds for 2.0 μ m continuous-wave laser irradiation. Single pulse radiant exposures were made at specified pulse durations of 0.1, 0.25, 0.5, 1.0, 2.0, and 4.0 s for spot 1 e 2 diameters of 1.17 mm and 4.02 mm . Threshold lesions were defined as the presence of a superficial surface whitening one hour after irradiation. Temperature measurements indicated that threshold peak temperatures were dependent on spot size and exposure duration. The exposure duration dependence of threshold average radiant exposure was described by an empirical power law equation: threshold radiant exposure [ J cm 2 ] = a × exposure duration [ s ] b .

© 2007 Optical Society of America

OCIS Codes
(110.6820) Imaging systems : Thermal imaging
(120.5630) Instrumentation, measurement, and metrology : Radiometry
(140.3330) Lasers and laser optics : Laser damage
(140.6810) Lasers and laser optics : Thermal effects
(330.3350) Vision, color, and visual optics : Vision - laser damage

ToC Category:
Lasers and Laser Optics

History
Original Manuscript: February 15, 2007
Revised Manuscript: June 6, 2007
Manuscript Accepted: June 17, 2007
Published: September 7, 2007

Virtual Issues
Vol. 2, Iss. 11 Virtual Journal for Biomedical Optics

Citation
Bo Chen, Jeffrey Oliver, Soumak Dutta, Grady H. Rylander III, Sharon L. Thomsen, and Ashley J. Welch, "Corneal minimal visible lesion thresholds for 2.0 μm laser radiation," J. Opt. Soc. Am. A 24, 3080-3088 (2007)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=josaa-24-10-3080

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